Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A5 | Q9Y345 | 7/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | NSD2 | O96028 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | MPO | P05164 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7514525 | 0.84 | KMT2A (0.45) | L3MBTL1HPGDRAB9AALDH1A1KMT2A | |
| SCHEMBL7513366 | 0.82 | CA1 (0.52) | SLC6A5GAAHPGDRAB9AALDH1A1 | |
| SCHEMBL23000227 | 0.73 | ALDH1A1 (0.54) | GAAHPGDRAB9AALDH1A1KDM4E | |
| SCHEMBL7515600 | 0.71 | ALDH1A1 (0.46) | LMNAGAAL3MBTL1RAB9AALDH1A1 | |
| SCHEMBL27879472 | 0.70 | PTGER4 (0.46) | LMNAGAAL3MBTL1HPGDRAB9A | |
| SCHEMBL7515603 | 0.68 | ALDH1A1 (0.47) | LMNAGAAHPGDRAB9AALDH1A1 | |
| SCHEMBL4007965 | 0.67 | TSHR (0.61) | GAAHPGDRAB9AALDH1A1CA1 | |
| SCHEMBL27879452 | 0.67 | GAA (0.58) | LMNAGAAL3MBTL1HPGDRAB9A | |
| Trifluoroacetic Acid SCHEMBL6382120 | 0.67 | CA1 (0.46) | SLC6A5GAAALDH1A1KMT2ACA1 | |
| Trifluoroacetic Acid SCHEMBL6377557 | 0.67 | CA1 (0.46) | SLC6A5GAAALDH1A1KMT2ACA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020032262-A1 | 2-aminoarylmethylamine solid support templated for preparation of highly functionalized heterocycle compounds | ZHANG JINFANG (US) | 2002-03-14 | — | — | US | disclosed |