Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7515595 | 0.84 | SLC6A5 (0.44) | KMT2AALDH1A1KDM4ESMN1; SMN2HPGD | |
| SCHEMBL7515852 | 0.83 | KMT2A (0.59) | KMT2AALDH1A1KDM4EMEN1SMN1; SMN2 | |
| SCHEMBL6377969 | 0.74 | KMT2A (0.59) | KMT2AALDH1A1KDM4EMEN1SMN1; SMN2 | |
| SCHEMBL7643262 | 0.74 | KMT2A (0.59) | KMT2AALDH1A1KDM4EMEN1SMN1; SMN2 | |
| SCHEMBL7598671 | 0.74 | HPGD (0.54) | KMT2AALDH1A1MEN1SMN1; SMN2CYP1A2 | |
| SCHEMBL1821856 | 0.74 | ALDH1A1 (0.49) | KMT2AALDH1A1KDM4ECYP1A2CYP3A4 | |
| SCHEMBL7514528 | 0.73 | SMN1; SMN2 (0.43) | KMT2AALDH1A1MEN1SMN1; SMN2NPC1 | |
| SCHEMBL16063183 | 0.73 | CASP6 (0.53) | HCAR3 | |
| SCHEMBL6559025 | 0.71 | SMN1; SMN2 (0.50) | KMT2AALDH1A1MEN1SMN1; SMN2NPC1 | |
| SCHEMBL4008493 | 0.70 | POLB (0.56) | KDM4EALOX5PTGES2POLBHCAR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020032262-A1 | 2-aminoarylmethylamine solid support templated for preparation of highly functionalized heterocycle compounds | ZHANG JINFANG (US) | 2002-03-14 | — | — | US | disclosed |