⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3673198 | 0.78 | NPC1 (0.33) | — | |
| SCHEMBL28382630 | 0.67 | — | — | |
| SCHEMBL28420841 | 0.66 | — | — | |
| SCHEMBL29691138 | 0.65 | CHRM3 (0.39) | — | |
| SCHEMBL31696082 | 0.64 | ALOX15 (0.31) | — | |
| SCHEMBL29054927 | 0.62 | — | — | |
| SCHEMBL27261747 | 0.62 | CYP11B1 (0.39) | — | |
| SCHEMBL11256936 | 0.62 | ALDH1A1 (0.31) | — | |
| SCHEMBL28189606 | 0.61 | — | — | |
| SCHEMBL11249563 | 0.61 | ALDH1A2 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1353689-A | Novel hydroxamic acid derivatives | DAIICHI PREC KAGAKU (JP) | 2002-06-12 | — | — | CN | disclosed |
| EP-1179529-A1 | NOVEL HYDROXAMIC ACID DERIVATIVES | Daiichi Fine Chemical Co., Ltd. (JP) | 2002-02-13 | — | — | EP | disclosed |
| CN-1284060-A | Novel metalloprotease inhibitors | FUJI YAKUHIN KOGYO KK (JP) | 2001-02-14 | — | — | CN | disclosed |
| EP-1038864-A1 | NOVEL METALLOPROTEINASE INHIBITORS | FUJI YAKUHIN KOGYO KABUSHIKI KAISHA (JP) | 2000-09-27 | — | — | EP | disclosed |