SCHEMBL7515879

SCHEMBL7515879

[CH2]CCOC(=O)C(Cl)(Cl)Cl

nearest known ligand 0.30

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.30
TP53 P04637 1/20 0.30
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6636802 0.86 ALDH1A1 (0.32) ALDH1A1TSHR
Ethylene SCHEMBL9816770 0.84 ALDH1A1 (0.33) ALDH1A1TP53TSHR
SCHEMBL1457249 0.84 ALDH1A1 (0.37) ALDH1A1TP53TSHR
SCHEMBL6642350 0.82 TSHR (0.39) ALDH1A1TSHR
SCHEMBL6638744 0.82 TSHR (0.39) ALDH1A1TSHR
SCHEMBL5525771 0.79
SCHEMBL11356672 0.77 ALDH1A1 (0.32) ALDH1A1TP53TSHR
SCHEMBL10072302 0.77 TSHR (0.41) ALDH1A1TP53TSHR
SCHEMBL9420651 0.77 ALDH1A1 (0.32) ALDH1A1TP53TSHR
SCHEMBL2112339 0.75 HTT (0.30)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6399731-B2 SYNTHESIZING POLYMERS USING PHOSPHOROUS-CONTAINING ADDITION-FRAGMENTATION CHAIN TRANSFER AGENTS; MOLECULAR WEIGHT CONTROL THE UNIVERSITY OF AKRON 2002-06-04 US disclosed
US-20020016424-A1 Synthesizing polymers using phosphorous-containing addition-fragmentation chain transfer agents; molecular weight control AKRON, THE UNIVERSITY OF 2002-02-07 US disclosed
WO-2000020465-A1 NOVEL CHAIN TRANSFER AGENTS THE UNIVERSITY OF AKRON (US) 2000-04-13 WO disclosed