SCHEMBL10072302

SCHEMBL10072302

O=C(OCCO)C(Cl)(Cl)Cl

nearest known ligand 0.41

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.41
ACHE P22303 1/20 0.33
MAPK1 P28482 1/20 0.32
ALDH1A1 P00352 1/20 0.32
TP53 P04637 1/20 0.32
MEN1 O00255 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1457249 0.86 ALDH1A1 (0.37) TSHRALDH1A1TP53
Thiourea SCHEMBL10617753 0.85 TSHR (0.32) TSHR
Ethylene SCHEMBL9816770 0.81 ALDH1A1 (0.33) TSHRALDH1A1TP53
SCHEMBL5776221 0.80 TSHR (0.38) TSHRACHEALDH1A1
SCHEMBL2786182 0.80 ACHE (0.39) TSHRACHEALDH1A1
SCHEMBL11356672 0.79 ALDH1A1 (0.32) TSHRALDH1A1TP53
SCHEMBL9420651 0.79 ALDH1A1 (0.32) TSHRALDH1A1TP53
SCHEMBL7515879 0.77 ALDH1A1 (0.30) TSHRALDH1A1TP53
SCHEMBL8746450 0.77 HCAR2 (0.40) TSHRACHEALDH1A1
SCHEMBL7081959 0.77 ALDH1A1 (0.32) MAPK1ALDH1A1TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107969730-B Preparation method of tobacco flavor microcapsule 北京亚美方舟科贸有限公司 2020-04-14 CN claimed
CN-107969730-B Preparation method of tobacco flavor microcapsule 北京亚美方舟科贸有限公司 2020-04-14 CN disclosed
WO-2012087531-A1 CATALYST COMPOSITION WITH ALKOXYALKYL ESTER INTERNAL ELECTRON DONOR AND POLYMER FROM SAME DOW GLOBAL TECHNOLOGIES LLC (US) 2012-06-28 WO disclosed
EP-0169715-B1 MODIFIED SUCCINIMIDES FOR USE IN LUBRICATING OILS AND HYDROCARBON FUELS CHEVRON RESEARCH AND TECHNOLOGY COMPANY (US) 1990-10-03 EP disclosed
US-4927551-A Lubricating oil compositions containing a combination of a modified succinimide and a Group II metal overbased sulfurized alkylphenol CHEVRON RESEARCH COMPANY (US) 1990-05-22 US disclosed
US-4904278-A OIL ADDITIVE CHEVRON RESEARCH COMPANY (US) 1990-02-27 US disclosed
US-4840744-A POLYAMINO ALKYL OR ALKENYL SUCCINIMIDES WHICH CONTAIN HYDROXY-FUNCTIONAL CARBAMATE GROUPS CHEVRON RESEARCH COMPANY (US) 1989-06-20 US disclosed
US-4802893-A OIL ADDITIVES; DISPERSANTS CHEVRON RESEARCH COMPANY (US) 1989-02-07 US disclosed
EP-0277222-A4 MODIFIED SUCCINIMIDES. CHEVRON RES (US) 1988-12-22 EP disclosed
EP-0277222-A1 MODIFIED SUCCINIMIDES. CHEVRON RES (US) 1988-08-10 EP disclosed
US-4747850-A Modified succinimides in fuel composition CHEVRON RESEARCH COMPANY (US) 1988-05-31 US disclosed
US-4746446-A DISPERSANTS FOR LUBRICATING OILS, GASOLINES, MARINE CRANKCASE OILS AND HYDRAULIC OILS; REACTING A POLYAMIND ALKENYL OR ALKYL SUCCINIMIDE WITH A BORON COMPOUND CHEVRON RESEARCH COMPANY (US) 1988-05-24 US disclosed
WO-1988001290-A1 MODIFIED SUCCINIMIDES CHEVRON RESEARCH COMPANY (US) 1988-02-25 WO disclosed
US-4664827-A Lubricant compositions containing modified succinimides CHEVRON RESEARCH COMPANY (US) 1987-05-12 US disclosed
US-4614522-A Fuel compositions containing modified succinimides (VI) CHEVRON RESEARCH COMPANY (US) 1986-09-30 US disclosed
US-4612132-A OIL AND FUEL ADDITIVES CHEVRON RESEARCH COMPANY (US) 1986-09-16 US disclosed
US-4608185-A Modified succinimides (VI) CHEVRON RESEARCH COMPANY (US) 1986-08-26 US disclosed
EP-0169715-A2 Modified succinimides for use in lubricating oils and hydrocarbon fuels CHEVRON RESEARCH AND TECHNOLOGY COMPANY (US) 1986-01-29 EP disclosed
US-4344881-A Process for making alkylene carbonates THE DOW CHEMICAL COMPANY (US) 1982-08-17 US disclosed
US-4293440-A HALOGENATED ALDEHYDE, SULFONATE, OR CARBOXYLATE HALLIBURTON COMPANY (US) 1981-10-06 US disclosed