Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY14 | Q15391 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | MMP13 | P45452 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | ACSL1 | P33121 | 1/20 | 0.38 |
| ▸ | XDH | P47989 | 1/20 | 0.38 |
| ▸ | CETP | P11597 | 2/20 | 0.37 |
| ▸ | CEPT1 | Q9Y6K0 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7515762 | 0.88 | TP53 (0.41) | TP53MAPTKMT2A | |
| SCHEMBL7518226 | 0.85 | TSHR (0.48) | P2RY14TP53MAPTRAB9AXDH | |
| SCHEMBL7886119 | 0.80 | LOXL2 (0.46) | TP53MAPTRAB9ACETP | |
| SCHEMBL11324879 | 0.75 | RAB9A (0.53) | P2RY14TP53MAPTRXFP1RAB9A | |
| SCHEMBL7512433 | 0.73 | POLB (0.41) | TP53MAPTRAB9AKMT2A | |
| SCHEMBL7520218 | 0.70 | KMT2A (0.56) | RAB9AKMT2A | |
| SCHEMBL3826911 | 0.68 | KMT2A (0.45) | MAPTKMT2A | |
| SCHEMBL12394367 | 0.68 | RAB9A (0.57) | TP53MAPTMMP13RAB9A | |
| SCHEMBL11329123 | 0.66 | KDM4E (0.48) | P2RY14TP53MAPTRAB9AKMT2A | |
| SCHEMBL4926605 | 0.66 | TPSAB1 (0.56) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1007518-A4 | SOLID AND LIQUID-PHASE SYNTHESIS OF BENZOXAZOLES AND BENZOTHIAZOLES AND THEIR USE | SEPRACOR INC (US) | 2002-11-06 | — | — | EP | disclosed |
| EP-1007518-A1 | SOLID AND LIQUID-PHASE SYNTHESIS OF BENZOXAZOLES AND BENZOTHIAZOLES AND THEIR USE | SEPRACOR, INC. (US) | 2000-06-14 | — | — | EP | disclosed |
| WO-1999009017-A1 | SOLID AND LIQUID-PHASE SYNTHESIS OF BENZOXAZOLES AND BENZOTHIAZOLES AND THEIR USE | SEPRACOR INC. (US) | 1999-02-25 | — | — | WO | disclosed |