Styrene

Styrene

SCHEMBL7516077

C=CCC(=C)C=C.C=Cc1ccccc1

nearest known ligand 0.56

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Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.56
TSHR P16473 2/20 0.56
TDP1 Q9NUW8 2/20 0.36
TP53 P04637 1/20 0.36
PAM P19021 1/20 0.34
AKT1 P31749 1/20 0.33
CYP3A4 P08684 1/20 0.33
CYP2C19 P33261 1/20 0.32
PDGFRB P09619 1/20 0.31
PDGFRA P16234 1/20 0.31
HDAC8 Q9BY41 1/20 0.31
TGM2 P21980 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Styrene SCHEMBL1359243 0.80 ALDH1A1 (0.56) ALDH1A1TSHRTDP1TP53AKT1
Styrene SCHEMBL8983397 0.78 ALDH1A1 (0.54) ALDH1A1TSHRPAMAKT1
Styrene SCHEMBL1904235 0.78 ALDH1A1 (0.58) ALDH1A1TSHRPAMAKT1CYP3A4
Styrene SCHEMBL4259704 0.78 ALDH1A1 (0.93) ALDH1A1TSHRTDP1TP53AKT1
Styrene SCHEMBL3223911 0.77 ALDH1A1 (0.52) ALDH1A1TSHRPAMAKT1CYP3A4
Styrene SCHEMBL195500 0.76 ALDH1A1 (0.70) ALDH1A1TSHRTDP1TP53CYP2C19
Styrene SCHEMBL9190171 0.76 ALDH1A1 (0.70) ALDH1A1TSHRTDP1TP53AKT1
SCHEMBL7600250 0.76 PAM (0.57) ALDH1A1TSHRPAMPDGFRBPDGFRA
Styrene SCHEMBL4986035 0.75 ALDH1A1 (1.00) ALDH1A1TSHRTDP1TP53AKT1
Styrene SCHEMBL9776790 0.75 ALDH1A1 (1.00) ALDH1A1TSHRTDP1TP53AKT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020083560-A1 Bagrabber a quick bag closure device and locking device MENNITTO ANTHONY (US) 2002-07-04 US disclosed