Styrene

Styrene

SCHEMBL1359243

C=CC(=C)CC.C=Cc1ccccc1.C=Cc1ccccc1

nearest known ligand 0.56

Full drug profile on Sugi Atlas →

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.56
TSHR P16473 1/20 0.56
TP53 P04637 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
CYP3A4 P08684 1/20 0.36
KDM1A O60341 1/20 0.35
HDAC8 Q9BY41 2/20 0.34
MEN1 O00255 2/20 0.34
KMT2A Q03164 2/20 0.34
NPC1 O15118 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
AKT1 P31749 1/20 0.33
LMNA P02545 1/20 0.33
TAS1R3 Q7RTX0 1/20 0.33
TAS1R1 Q7RTX1 1/20 0.33
NR1I2 O75469 1/20 0.33
RELA Q04206 1/20 0.32
ATM Q13315 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Styrene SCHEMBL3717971 0.82 ALDH1A1 (0.54) ALDH1A1TSHRTP53TDP1CYP3A4
Styrene SCHEMBL3206232 0.81 ALDH1A1 (0.70) ALDH1A1TSHRTP53TDP1CYP3A4
Styrene SCHEMBL28211071 0.80 ALDH1A1 (0.78) ALDH1A1TSHRTP53TDP1HDAC8
Styrene SCHEMBL21314201 0.80 ALDH1A1 (0.56) ALDH1A1TSHRTP53TDP1CYP3A4
Styrene SCHEMBL7516077 0.80 ALDH1A1 (0.56) ALDH1A1TSHRTP53TDP1CYP3A4
Styrene SCHEMBL23036036 0.80 ALDH1A1 (0.56) ALDH1A1TSHRTP53TDP1CYP3A4
Styrene SCHEMBL16875725 0.79 ALDH1A1 (0.50) ALDH1A1TSHRTP53TDP1CYP3A4
Styrene SCHEMBL15142056 0.79 ALDH1A1 (0.50) ALDH1A1TSHRTP53TDP1CYP3A4
Styrene SCHEMBL27551584 0.79 ALDH1A1 (0.61) ALDH1A1TSHRTDP1HDAC8MEN1
Styrene SCHEMBL5914572 0.79 ALDH1A1 (0.67) ALDH1A1TSHRTP53TDP1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9021990-B2 Pet toy and method of making a pet toy DOSKOCIL MANUFACTURING COMPANY, INC. (US) 2015-05-05 US disclosed
US-20140130750-A1 DESTRUCTION RESISTANT PET TOYS JW PET COMPANY, INC. (US) 2014-05-15 US disclosed
US-20110277696-A1 PET TOY AND METHOD OF MAKING A PET TOY J.W. PET COMPANY, INC. (US) 2011-11-17 US disclosed