Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP1 | O94782 | 1/20 | 0.34 |
| ▸ | WDR48 | Q8TAF3 | 1/20 | 0.34 |
| ▸ | CLK4 | Q9HAZ1 | 6/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.32 |
| ▸ | PRKCI | P41743 | 3/20 | 0.32 |
| ▸ | DYRK1A | Q13627 | 3/20 | 0.31 |
| ▸ | CLK1 | P49759 | 2/20 | 0.31 |
| ▸ | CLK2 | P49760 | 2/20 | 0.31 |
| ▸ | DYRK1B | Q9Y463 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.30 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.30 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.30 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5128249 | 0.96 | USP1 (0.36) | USP1WDR48CLK4GAARXFP1 | |
| SCHEMBL5809508 | 0.91 | GAA (0.40) | USP1WDR48CLK4GAARXFP1 | |
| SCHEMBL7514448 | 0.91 | BCDIN3D (0.40) | CHRM4 | |
| SCHEMBL5814655 | 0.89 | CHRM4 (0.40) | USP1WDR48CLK4CHRM4DYRK1A | |
| SCHEMBL5130870 | 0.89 | GAA (0.42) | USP1WDR48CLK4GAARXFP1 | |
| SCHEMBL5812974 | 0.88 | CHRM4 (0.40) | CLK4GAACHRM4DYRK1ALMNA | |
| SCHEMBL5128434 | 0.86 | BCDIN3D (0.42) | CHRM4 | |
| SCHEMBL5126310 | 0.86 | CHRM4 (0.41) | GAARXFP1CHRM4PRKCIHPGD | |
| SCHEMBL5124136 | 0.85 | CHRM4 (0.42) | CLK4CHRM4DYRK1ACLK1CLK2 | |
| SCHEMBL5809171 | 0.84 | PRKCI (0.48) | PRKCI |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0920431-A1 | THIENOPYRIMIDINES | MERCK PATENT GmbH (DE) | 1999-06-09 | — | — | EP | disclosed |
| WO-1998006722-A1 | THIENOPYRIMIDINES | MERCK PATENT GMBH (DE) | 1998-02-19 | — | — | WO | disclosed |