SCHEMBL7516130

SCHEMBL7516130

O=C(Cl)CC(C(=O)Cl)C(CC(=O)Cl)C(=O)Cl

nearest known ligand 0.32

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.32
ALDH1A1 P00352 1/20 0.32
TSHR P16473 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22339943 0.75
SCHEMBL652869 0.75
SCHEMBL9868411 0.73 ALDH1A1 (0.38) TDP1ALDH1A1TSHR
SCHEMBL12073 0.73
SCHEMBL4962965 0.73 ALDH1A1 (0.53) TDP1ALDH1A1TSHR
SCHEMBL1741585 0.73 TSHR (0.32) TSHR
SCHEMBL14879116 0.71 ALDH1A1 (0.32) TDP1ALDH1A1TSHR
SCHEMBL427600 0.71
SCHEMBL3506045 0.71
SCHEMBL8841243 0.71 GRIK1 (0.32) TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5160619-A Crosslinked polyamide NITTO DENKO CORPORATION (JP) 1992-11-03 US claimed
US-10351513-B2 Thickening and stabilizing agent, and thickening and stabilizing composition using same DAICEL CORPORATION (JP) 2019-07-16 US disclosed
US-20170320814-A1 THICKENING AND STABILIZING AGENT, AND THICKENING AND STABILIZING COMPOSITION USING SAME DAICEL CORPORATION (JP) 2017-11-09 US disclosed
EP-3222611-A1 THICKENING AND STABILIZING AGENT, AND THICKENING AND STABILIZING COMPOSITION USING SAME Daicel Corporation (JP) 2017-09-27 EP disclosed
US-20150361257-A1 METHOD FOR PRODUCING SUBSTRATE HAVING PATTERN AND RESIN COMPOSITION FOR HYDROFLUORIC ACID ETCHING NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2015-12-17 US disclosed
US-20020137659-A1 Reaction products of polycarboxylic acids derivatives thereof COGNIS CORPORATION (COGNIS CORP.) 2002-09-26 US disclosed
WO-2002050237-A1 REACTION PRODUCTS OF POLYCARBOXYLIC ACIDS AND DERIVATIVES THEREOF COGNIS CORPORATION (US) 2002-06-27 WO disclosed
US-5616249-A USING ALL ALIPHATIC POLYAMIDES FROM POLYAMINO COMPOUNDS AND COMPOUNDS HAVING TWO OR MORE ACID HALIDE GROUPS IONICS, INCORPORATED (US) 1997-04-01 US disclosed
US-5510527-A Acid chloride NITTO DENKO CORPORATION (JP) 1996-04-23 US disclosed
US-5336409-A Composite reverse osmosis membrane and novel acid chloride NITTO DENKO CORPORATION (JP) 1994-08-09 US disclosed
US-5160619-A Crosslinked polyamide NITTO DENKO CORPORATION (JP) 1992-11-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10351513-B2 Thickening and stabilizing agent, and thickening and stabilizing composition using same CNOT1, GRN, HRH1 TDP1 850/4885ALDH1A1 2626/4885TSHR 3925/4885
US-20170320814-A1 THICKENING AND STABILIZING AGENT, AND THICKENING AND STABILIZING COMPOSITION USING SAME CNOT1, GRN, HRH1 TDP1 850/4885ALDH1A1 2626/4885TSHR 3925/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.