SCHEMBL8841243

SCHEMBL8841243

O=C(Cl)CC(CC(CC(=O)Cl)C(=O)Cl)C(=O)Cl

nearest known ligand 0.32

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
GRIK1 P39086 1/20 0.32
GRIK2 Q13002 1/20 0.32
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1741585 0.90 TSHR (0.32) TSHR
SCHEMBL150292 0.80 TSHR (0.38) TSHR
SCHEMBL8841262 0.78 TSHR (0.36) TSHR
SCHEMBL9230319 0.76
SCHEMBL28225093 0.76
SCHEMBL8710828 0.75 GRIK1 (0.39) GRIK1GRIK2
SCHEMBL14744089 0.75 FOLH1 (0.30)
SCHEMBL28646331 0.73 SLC22A6 (0.30)
SCHEMBL7516130 0.71 TDP1 (0.32) TSHR
SCHEMBL8653713 0.69 SLC1A3 (0.52) GRIK1GRIK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5160619-A Crosslinked polyamide NITTO DENKO CORPORATION (JP) 1992-11-03 US claimed
US-5616249-A USING ALL ALIPHATIC POLYAMIDES FROM POLYAMINO COMPOUNDS AND COMPOUNDS HAVING TWO OR MORE ACID HALIDE GROUPS IONICS, INCORPORATED (US) 1997-04-01 US disclosed
US-5510527-A Acid chloride NITTO DENKO CORPORATION (JP) 1996-04-23 US disclosed
US-5336409-A Composite reverse osmosis membrane and novel acid chloride NITTO DENKO CORPORATION (JP) 1994-08-09 US disclosed
EP-0556569-A2 Composite reverse osmosis membrane and novel acid chloride NITTO DENKO CORPORATION (JP) 1993-08-25 EP disclosed
US-5160619-A Crosslinked polyamide NITTO DENKO CORPORATION (JP) 1992-11-03 US disclosed