SCHEMBL1741585

SCHEMBL1741585

O=C(Cl)CC(CC(=O)Cl)C(=O)Cl

nearest known ligand 0.32

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8841243 0.90 GRIK1 (0.32) TSHR
SCHEMBL150292 0.83 TSHR (0.38) TSHR
SCHEMBL8841262 0.81 TSHR (0.36) TSHR
SCHEMBL28225093 0.79
SCHEMBL9230319 0.79
SCHEMBL8710828 0.77 GRIK1 (0.39)
SCHEMBL14744089 0.77 FOLH1 (0.30)
SCHEMBL28646331 0.75 SLC22A6 (0.30)
SCHEMBL7516130 0.73 TDP1 (0.32) TSHR
SCHEMBL8865611 0.72 CA2 (0.50) TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 114 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12508565-B2 Polyamide microcapsules FIRMENICH SA (CH) 2025-12-30 US claimed
US-20240050330-A1 PROCESS FOR PREPARING POLYESTER MICROCAPSULES FIRMENICH SA (CH) 2024-02-15 US claimed
US-20240050917-A1 PROCESS FOR PREPARING POLYESTER MICROCAPSULES FIRMENICH SA (CH) 2024-02-15 US claimed
EP-4196257-A1 PROCESS FOR PREPARING POLYESTER MICROCAPSULES Firmenich SA (CH) 2023-06-21 EP claimed
EP-4178715-A1 PROCESS FOR PREPARING POLYESTER MICROCAPSULES Firmenich SA (CH) 2023-05-17 EP claimed
EP-4164783-A1 POLYAMIDE MICROCAPSULES Firmenich SA (CH) 2023-04-19 EP claimed
US-20230105666-A1 POLYAMIDE MICROCAPSULES FIRMENICH SA (CH) 2023-04-06 US claimed
WO-2022136008-A1 PROCESS FOR PREPARING POLYESTER MICROCAPSULES FIRMENICH SA (CH) 2022-06-30 WO claimed
WO-2022136007-A1 PROCESS FOR PREPARING POLYESTER MICROCAPSULES FIRMENICH SA (CH) 2022-06-30 WO claimed
WO-2021254931-A1 POLYAMIDE MICROCAPSULES FIRMENICH SA (CH) 2021-12-23 WO claimed
US-5160619-A Crosslinked polyamide NITTO DENKO CORPORATION (JP) 1992-11-03 US claimed
WO-2026087780-A1 CORE-SHELL MICROCAPSULES FIRMENICH SA (CH) 2026-04-30 WO disclosed
EP-4713129-A1 ORGANOSILICON-BASED MICROCAPSULES Firmenich SA (CH) 2026-03-25 EP disclosed
EP-4688246-A1 COACERVATE CORE-SHELL MICROCAPSULES Firmenich SA (CH) 2026-02-11 EP disclosed
US-20260034034-A1 COMPOSITE MICROCAPSULES FIRMENICH & CIE (CH) 2026-02-05 US disclosed
US-5160619-A Crosslinked polyamide NITTO DENKO CORPORATION (JP) 1992-11-03 US disclosed
EP-0468323-A1 Improved microcapsules BAYER AG (DE) 1992-01-29 EP disclosed
EP-0254369-B1 BRANCHED POLYCARBONATES CONTAINING ALIPHATIC POLICARBOXYLIC ACIDS OR DERIVATIVES THEREOF, AND PROCESS FOR THEIR PREPARATION ECP ENICHEM POLIMERI S.r.l. (IT) 1992-01-29 EP disclosed
US-4795797-A Branched polycarbonate from aliphatic polyicarboxylic acids or derivatives thereof, and process for their preparation ENICHEM TECNORESINE S.P.A. (IT) 1989-01-03 US disclosed
EP-0254369-A2 Branched polycarbonates containing aliphatic policarboxylic acids or derivatives thereof, and process for their preparation ECP ENICHEM POLIMERI S.r.l. (IT) 1988-01-27 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260034034-A1 COMPOSITE MICROCAPSULES S100P, HAMP, PCTP TSHR 4379/4885
US-20240050330-A1 PROCESS FOR PREPARING POLYESTER MICROCAPSULES CHMP4B, EXOSC9, F5 TSHR 4296/4885
US-20240050917-A1 PROCESS FOR PREPARING POLYESTER MICROCAPSULES CHMP4B, EXOSC9, F5 TSHR 4296/4885
US-12508565-B2 Polyamide microcapsules PHGDH, GLUL, PCCA TSHR 4282/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.