Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNP | P00491 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.52 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.52 |
| ▸ | NT5E | P21589 | 7/20 | 0.50 |
| ▸ | ADORA3 | P0DMS8 | 4/20 | 0.45 |
| ▸ | UPP1 | Q16831 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA4 | P22748 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.42 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.42 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.42 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.41 |
| ▸ | CD99 | P14209 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL37272 | 0.93 | PNP (0.54) | PNPLMNATP53HTTPDE4D | |
| SCHEMBL1219170 | 0.93 | PNP (0.54) | PNPLMNATP53HTTPDE4D | |
| SCHEMBL37437 | 0.93 | PNP (0.54) | PNPLMNATP53HTTPDE4D | |
| SCHEMBL9393705 | 0.92 | LMNA (0.49) | PNPLMNATP53HTTPDE4D | |
| SCHEMBL6559406 | 0.92 | LMNA (0.49) | PNPLMNATP53HTTPDE4D | |
| SCHEMBL6559404 | 0.92 | LMNA (0.49) | PNPLMNATP53HTTPDE4D | |
| SCHEMBL7200818 | 0.92 | LMNA (0.49) | PNPLMNATP53HTTPDE4D | |
| SCHEMBL7915780 | 0.89 | UPP1 (0.44) | PNPLMNATP53HTTPDE4D | |
| SCHEMBL7915783 | 0.89 | UPP1 (0.44) | PNPLMNATP53HTTPDE4D | |
| SCHEMBL9335172 | 0.87 | ABCB1 (0.53) | P2RY1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020052491-A1 | Method for the production of 2-chloro-2' -deoxyadenosine (cladribine) and its 3,5-di-O-p-toluoyl derivative | GERSZBERG SZEPSEL (AR) | 2002-05-02 | — | — | US | claimed |
| WO-2000064918-A1 | METHOD FOR THE PRODUCTION OF 2-CHLORO-2'-DEOXYADENOSINE (CLADRIBINE) AND ITS 3,5-DI-O-p-TOLUOYL DERIVATIVE | STERRENBELD BIOTECHNOLOGIE NORTH AMERICA, INC. (US) | 2000-11-02 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020052491-A1 | Method for the production of 2-chloro-2' -deoxyadenosine (cladribine) and its 3,5-di-O-p-toluoyl derivative | MTAP, TPMT, DCTD | PNP 4/4885LMNA 3828/4885TP53 2903/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.