Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 1/20 | 0.53 |
| ▸ | GSK3A | P49840 | 2/20 | 0.50 |
| ▸ | RPS6KA3 | P51812 | 2/20 | 0.50 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | ENPP1 | P22413 | 3/20 | 0.46 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.46 |
| ▸ | P2RX3 | P56373 | 2/20 | 0.46 |
| ▸ | P2RX4 | Q99571 | 2/20 | 0.46 |
| ▸ | P2RX2 | Q9UBL9 | 2/20 | 0.46 |
| ▸ | P2RX6 | O15547 | 1/20 | 0.44 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.44 |
| ▸ | P2RX5 | Q93086 | 1/20 | 0.44 |
| ▸ | P2RY11 | Q96G91 | 1/20 | 0.44 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.44 |
| ▸ | HSP90B1 | P14625 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9335175 | 1.00 | ABCB1 (0.53) | ABCB1GSK3ARPS6KA3MAPK14POLB | |
| SCHEMBL532524 | 0.91 | P2RX3 (0.55) | ABCB1GSK3ARPS6KA3MAPK14POLB | |
| SCHEMBL532525 | 0.91 | P2RX3 (0.55) | ABCB1GSK3ARPS6KA3MAPK14POLB | |
| SCHEMBL8790811 | 0.90 | UPP1 (0.45) | ABCB1GSK3ARPS6KA3MAPK14POLB | |
| SCHEMBL8671208 | 0.90 | UPP1 (0.45) | ABCB1GSK3ARPS6KA3MAPK14POLB | |
| SCHEMBL8671210 | 0.90 | UPP1 (0.45) | ABCB1GSK3ARPS6KA3MAPK14POLB | |
| SCHEMBL7516274 | 0.87 | PNP (0.52) | P2RY1 | |
| SCHEMBL9538630 | 0.87 | P2RY1 (0.43) | ABCB1P2RY1 | |
| SCHEMBL17106838 | 0.85 | METTL3 (0.49) | ABCB1 | |
| SCHEMBL17106835 | 0.85 | METTL3 (0.49) | ABCB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0350292-B1 | Process for preparing 2'-deoxy-beta-adenosine | JAPAN TOBACCO INC (JP) | 1994-05-04 | — | — | EP | disclosed |
| US-5262531-A | Process for preparing 2'-deoxy-β-adenosine | JAPAN TOBACCO, INC. (JP) | 1993-11-16 | — | — | US | disclosed |
| EP-0350292-A2 | Process for preparing 2'-deoxy-beta-adenosine | Japan Tobacco Inc. (JP) | 1990-01-10 | — | — | EP | disclosed |