SCHEMBL7516283

SCHEMBL7516283

NC(=Cc1ccccc1)c1ccc(C=Cc2ccccc2)c(S(=O)(=O)O)c1S(=O)(=O)O

nearest known ligand 0.36

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 1/20 0.36
HTR2A P28223 4/20 0.36
HTR2C P28335 4/20 0.36
KCNH2 Q12809 2/20 0.35
DHFR P00374 1/20 0.33
SIRT2 Q8IXJ6 1/20 0.33
NFE2L2 Q16236 1/20 0.33
PTPN1 P18031 2/20 0.32
MCL1 Q07820 1/20 0.32
CYP19A1 P11511 1/20 0.32
MAOA P21397 1/20 0.32
MAOB P27338 1/20 0.32
PELI1 Q96FA3 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1719173 0.78 TRPA1 (0.41) TRPA1HTR2AHTR2CKCNH2DHFR
(Z)-1,2-Diphenylethene SCHEMBL28122368 0.74 TRPA1 (0.40) TRPA1HTR2AHTR2CKCNH2DHFR
SCHEMBL157941 0.74 TRPA1 (0.40) TRPA1HTR2AHTR2CKCNH2DHFR
SCHEMBL7590546 0.72 PELI1 (0.40) TRPA1HTR2AHTR2CKCNH2NFE2L2
SCHEMBL722164 0.72 TRPA1 (0.44) TRPA1DHFRNFE2L2CYP19A1MAOA
SCHEMBL29413345 0.72 TRPA1 (0.44) TRPA1DHFRNFE2L2CYP19A1MAOA
SCHEMBL285312 0.71 TRPA1 (0.47) TRPA1HTR2AHTR2CKCNH2NFE2L2
SCHEMBL2528153 0.71 TRPA1 (0.47) TRPA1HTR2AHTR2CKCNH2NFE2L2
SCHEMBL8076471 0.71 TRPA1 (0.43) TRPA1HTR2AHTR2CKCNH2DHFR
SCHEMBL8076468 0.71 TRPA1 (0.43) TRPA1DHFRNFE2L2CYP19A1MAOA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2001092217-A3 PROCESS FOR THE PREPARATION OF AMIDOSTYRYLSTILBENE-DISULPHONIC ACID COMPOUNDS AND NOVEL AMIDOSTYRYLSTILBENE-DISULPHONIC ACID COMPOUNDS AND THEIR USE AS FLUORESCENT WHITENING AGENTS CIBA SC HOLDING AG (CH) 2002-05-16 WO disclosed
WO-2001092217-A2 PROCESS FOR THE PREPARATION OF AMIDOSTYRYLSTILBENE-DISULPHONIC ACID COMPOUNDS AND NOVEL AMIDOSTYRYLSTILBENE-DISULPHONIC ACID COMPOUNDS AND THEIR USE AS FLUORESCENT WHITENING AGENTS CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2001-12-06 WO disclosed
WO-2001092217-A2 PROCESS FOR THE PREPARATION OF AMIDOSTYRYLSTILBENE-DISULPHONIC ACID COMPOUNDS AND NOVEL AMIDOSTYRYLSTILBENE-DISULPHONIC ACID COMPOUNDS AND THEIR USE AS FLUORESCENT WHITENING AGENTS CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2001-12-06 WO disclosed