SCHEMBL2528153

SCHEMBL2528153

O=S(=O)(O)c1c(/C=C/c2ccccc2)cccc1-c1cccc(/C=C/c2ccccc2)c1S(=O)(=O)O

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 2/20 0.47
NFE2L2 Q16236 5/20 0.43
LMNA P02545 2/20 0.39
PPARG P37231 1/20 0.39
NR1H2 P55055 1/20 0.38
HDAC3 O15379 1/20 0.37
TNKS O95271 1/20 0.37
HDAC4 P56524 1/20 0.37
HDAC1 Q13547 1/20 0.37
HCAR2 Q8TDS4 1/20 0.37
HDAC7 Q8WUI4 1/20 0.37
HDAC2 Q92769 1/20 0.37
HDAC10 Q969S8 1/20 0.37
HDAC11 Q96DB2 1/20 0.37
HDAC8 Q9BY41 1/20 0.37
TNKS2 Q9H2K2 1/20 0.37
HDAC6 Q9UBN7 1/20 0.37
HDAC9 Q9UKV0 1/20 0.37
HDAC5 Q9UQL6 1/20 0.37
PLIN1 O60240 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10766929 0.97 TRPA1 (0.44) TRPA1NFE2L2LMNAPPARGNR1H2
SCHEMBL285312 0.86 TRPA1 (0.47) TRPA1NFE2L2LMNAPPARGNR1H2
SCHEMBL3936740 0.85 TRPA1 (0.46) TRPA1NFE2L2LMNAPPARGNR1H2
SCHEMBL5145247 0.85 TRPA1 (0.46) TRPA1NFE2L2LMNAPPARGNR1H2
Ammonia Solution, Strong SCHEMBL27680778 0.85 TRPA1 (0.46) TRPA1NFE2L2LMNAPPARGNR1H2
SCHEMBL2528157 0.85 TRPA1 (0.40) TRPA1NFE2L2LMNAPPARGNR1H2
SCHEMBL566321 0.84 TRPA1 (0.39) TRPA1NFE2L2NR1H2SMN1; SMN2HTR2A
SCHEMBL29413345 0.83 TRPA1 (0.44) TRPA1NFE2L2LMNAPPARGNR1H2
SCHEMBL722164 0.83 TRPA1 (0.44) TRPA1NFE2L2LMNAPPARGNR1H2
SCHEMBL8076471 0.82 TRPA1 (0.43) TRPA1NFE2L2LMNAPPARGMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-11158410-A None JP disclosed
US-20230371513-A1 PHOTOSTABLE COMPOSITION AND METHOD OF REDUCING OR CONTROLLING WEED POPULATION APPLYING SAID COMPOSITION UPL DO BRASIL INDUSTRIA E COMERCIO DE INSUMOS AGROPECUARIOS S.A. (BR) 2023-11-23 US disclosed
WO-2022067414-A1 PHOTOSTABLE COMPOSITION AND METHOD OF REDUCING OR CONTROLLING WEED POPULATION APPLYING SAID COMPOSITION UPL DO BRASIL INDUSTRIA E COMERCIO DE INSUMOS AGROPECUARIOS S.A. (BR) 2022-04-07 WO disclosed
US-9125411-B2 UV absorbers for reducing the E/Z isomerization of pesticides BASF SE (DE) 2015-09-08 US disclosed
EP-2557917-A1 UV ABSORBER FOR REDUCING THE E/Z ISOMERIZATION OF PESTICIDES BASF SE (DE) 2013-02-20 EP disclosed
WO-2011141264-A1 UV ABSORBER FOR REDUCING THE E/Z ISOMERIZATION OF PESTICIDES BASF SE (DE) 2011-11-17 WO disclosed
US-20110257265-A1 UV Absorbers for Reducing the E/Z Isomerization of Pesticides BASF SE (DE) 2011-10-20 US disclosed
WO-2008012183-A1 COLOURED GRANULAR MATERIAL HENKEL AG & CO. KGAA (DE) 2008-01-31 WO disclosed
JP-H11158410-A OPTICAL WHITENING AGENT CIBA SPECIALTY CHEM HOLDING INC 1999-06-15 JP disclosed
US-4908040-A Contains nitrile as shading dye; fabric bleaching agent CIBA-GEIGY CORPORATION (US) 1990-03-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110257265-A1 UV Absorbers for Reducing the E/Z Isomerization of Pesticides DDT, PIN1, ERCC4 TRPA1 562/4885NFE2L2 704/4885LMNA 910/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.