Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 6/20 | 0.69 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.49 |
| ▸ | TRPV1 | Q8NER1 | 5/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7524387 | 0.82 | MTNR1A (1.00) | MTNR1A | |
| SCHEMBL7523264 | 0.81 | MTNR1A (0.71) | MTNR1A | |
| SCHEMBL7526194 | 0.80 | MTNR1A (0.68) | MTNR1AGAATRPV1ALDH1A1 | |
| SCHEMBL7526968 | 0.79 | MTNR1A (0.73) | MTNR1A | |
| SCHEMBL7520035 | 0.78 | MTNR1A (1.00) | MTNR1A | |
| SCHEMBL6649870 | 0.77 | MTNR1A (0.71) | MTNR1AMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL7520573 | 0.76 | MTNR1A (0.73) | MTNR1A | |
| SCHEMBL9080237 | 0.75 | MEN1 (0.83) | MEN1KMT2AGAAEPHX2TRPV1 | |
| SCHEMBL2942358 | 0.75 | MEN1 (0.96) | MEN1KMT2AGAAEPHX2TRPV1 | |
| SCHEMBL7523147 | 0.74 | MTNR1A (1.00) | MTNR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0873993-B1 | Heterocyclic compounds, process for their preparation and pharmaceutical compositions containing them | SERVIER LAB (FR) | 2002-02-20 | — | — | EP | disclosed |
| US-5919814-A | Heterocyclic compounds | ADIR ET COMPAGNIE (FR) | 1999-07-06 | — | — | US | disclosed |
| EP-0873993-A1 | Heterocyclic compounds, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1998-10-28 | — | — | EP | disclosed |