Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 7/20 | 0.71 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | LTB4R | Q15722 | 6/20 | 0.43 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.43 |
| ▸ | F13A1 | P00488 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.42 |
| ▸ | WNT3A | P56704 | 1/20 | 0.42 |
| ▸ | LTB4R2 | Q9NPC1 | 5/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6649870 | 0.95 | MTNR1A (0.71) | MTNR1AKDM4ELTB4RROCK2CYP3A4 | |
| SCHEMBL3430852 | 0.89 | MTNR1A (0.62) | MTNR1AKDM4EROCK2CYP3A4CYP2D6 | |
| SCHEMBL9160573 | 0.88 | MTNR1A (0.56) | MTNR1ALTB4RF13A1MAPTRXFP1 | |
| SCHEMBL7524387 | 0.83 | MTNR1A (1.00) | MTNR1AROCK2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL8481573 | 0.81 | MTNR1A (0.66) | MTNR1ACYP3A4CYP2D6CYP2C9CTNNB1 | |
| SCHEMBL7516488 | 0.81 | MTNR1A (0.69) | MTNR1A | |
| SCHEMBL7526419 | 0.80 | MTNR1A (0.61) | MTNR1AKDM4EROCK2CYP3A4CYP2D6 | |
| SCHEMBL3639598 | 0.80 | MTNR1A (0.59) | MTNR1AKDM4EROCK2CYP3A4CYP2D6 | |
| SCHEMBL7520035 | 0.79 | MTNR1A (1.00) | MTNR1AROCK2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL27911302 | 0.79 | MTNR1A (0.48) | MTNR1AKDM4EROCK2CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0873993-B1 | Heterocyclic compounds, process for their preparation and pharmaceutical compositions containing them | SERVIER LAB (FR) | 2002-02-20 | — | — | EP | disclosed |
| US-5919814-A | Heterocyclic compounds | ADIR ET COMPAGNIE (FR) | 1999-07-06 | — | — | US | disclosed |
| EP-0873993-A1 | Heterocyclic compounds, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1998-10-28 | — | — | EP | disclosed |