Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 2/20 | 0.64 |
| ▸ | MAPT | P10636 | 6/20 | 0.52 |
| ▸ | RAB9A | P51151 | 3/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | GLA | P06280 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.51 |
| ▸ | GFER | P55789 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | PLAU | P00749 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | F2 | P00734 | 1/20 | 0.50 |
| ▸ | F10 | P00742 | 1/20 | 0.50 |
| ▸ | PLAT | P00750 | 1/20 | 0.50 |
| ▸ | EGFR | P00533 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5925259 | 0.91 | MAPT (0.59) | HDAC1MAPTRAB9APOLBKDM4E | |
| SCHEMBL5925289 | 0.85 | KDM4E (0.51) | HDAC1MAPTRAB9APOLBKDM4E | |
| SCHEMBL10289025 | 0.84 | POLB (0.61) | MAPTRAB9APOLBKDM4EGLA | |
| SCHEMBL7516604 | 0.84 | PLAU (0.52) | HDAC1MAPTRAB9APOLBKDM4E | |
| SCHEMBL6592828 | 0.82 | MAPT (0.61) | MAPTRAB9AALDH1A1SMN1; SMN2GFER | |
| SCHEMBL9954063 | 0.82 | JAK2 (0.54) | RAB9AKDM4EGLAALDH1A1SMN1; SMN2 | |
| SCHEMBL27194309 | 0.80 | KMT2A (0.55) | HDAC1MAPTRAB9AKDM4EGLA | |
| SCHEMBL14345245 | 0.79 | PLAU (0.44) | HDAC1MAPTRAB9APOLBKDM4E | |
| SCHEMBL6593023 | 0.79 | FADS1 (0.67) | HDAC1MAPTRAB9APOLBALDH1A1 | |
| SCHEMBL15551746 | 0.78 | HDAC1 (1.00) | HDAC1MAPTRAB9APOLBKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001021160-B1 | CARBOXYMIDE AND ANILINE DERIVATIVES AS SELECTIVE INHIBITORS OF PATHOGENS | AXXIMA PHARMACEUTICALS AG (DE) | 2002-05-30 | — | — | WO | claimed |