Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAU | P00749 | 2/20 | 0.52 |
| ▸ | F2 | P00734 | 1/20 | 0.52 |
| ▸ | F10 | P00742 | 1/20 | 0.52 |
| ▸ | PLAT | P00750 | 1/20 | 0.52 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | RAB9A | P51151 | 3/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.50 |
| ▸ | GFER | P55789 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | EGFR | P00533 | 1/20 | 0.49 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7516613 | 0.84 | HDAC1 (0.64) | PLAUF2F10PLATHDAC1 | |
| SCHEMBL7452993 | 0.77 | SIRT2 (0.48) | HDAC1MAPTRAB9APOLBALDH1A1 | |
| SCHEMBL25492919 | 0.76 | ALDH1A1 (0.55) | HDAC1MAPTRAB9AALDH1A1NPC1 | |
| SCHEMBL26170005 | 0.76 | ALDH1A1 (0.69) | HDAC1MAPTRAB9APOLBALDH1A1 | |
| SCHEMBL9674 | 0.75 | MAPT (0.81) | MAPTRAB9APOLBALDH1A1SMN1; SMN2 | |
| SCHEMBL2344362 | 0.75 | DGAT1 (0.67) | PLAUMAPTPOLBALDH1A1SMN1; SMN2 | |
| SCHEMBL9246171 | 0.73 | MEN1 (0.55) | PLAUF2F10PLATMAPT | |
| SCHEMBL5925259 | 0.73 | MAPT (0.59) | PLAUF2F10PLATHDAC1 | |
| Dibromsalan SCHEMBL29496335 | 0.71 | PLAU (0.73) | PLAUF2F10PLATMAPT | |
| SCHEMBL7376765 | 0.71 | SIRT2 (0.59) | HDAC1MAPTRAB9APOLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001021160-B1 | CARBOXYMIDE AND ANILINE DERIVATIVES AS SELECTIVE INHIBITORS OF PATHOGENS | AXXIMA PHARMACEUTICALS AG (DE) | 2002-05-30 | — | — | WO | claimed |