Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.36 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.30 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL172842 | 0.90 | ALDH1A1 (0.38) | ALDH1A1KDM4ETSHRL3MBTL1 | |
| SCHEMBL25489245 | 0.83 | ALDH1A1 (0.37) | ALDH1A1TRPV1TRPA1KDM4ETSHR | |
| SCHEMBL4611588 | 0.82 | ALDH1A1 (0.34) | ALDH1A1TRPV1TRPA1KDM4E | |
| SCHEMBL11030766 | 0.82 | ALDH1A1 (0.40) | ALDH1A1KDM4ETSHRL3MBTL1DEGS1 | |
| SCHEMBL13864131 | 0.82 | ALDH1A1 (0.40) | ALDH1A1KDM4ETSHRL3MBTL1DEGS1 | |
| SCHEMBL5159311 | 0.82 | ALDH1A1 (0.40) | ALDH1A1KDM4ETSHRL3MBTL1DEGS1 | |
| SCHEMBL5163869 | 0.82 | ALDH1A1 (0.40) | ALDH1A1KDM4ETSHRL3MBTL1DEGS1 | |
| SCHEMBL10498184 | 0.80 | LMNA (0.43) | ALDH1A1KDM4EDNM1 | |
| SCHEMBL14241089 | 0.80 | LMNA (0.43) | ALDH1A1KDM4EDNM1 | |
| SCHEMBL12353671 | 0.80 | LMNA (0.43) | ALDH1A1KDM4EDNM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0887072-B1 | Use of sulfites and metabisulfites for the manufacturing of cosmetic or pharmaceutical, in particular dermatological compositions having an inhibitory effect on melanogenesis or a skin whitening activity | COLETICA (FR) | 2002-01-09 | — | — | EP | disclosed |
| EP-0887072-A1 | Use of sulfites and meta bisulfites, for the manufacturing of cosmetic or pharmaceutical compositions, principally for dermatologig, having an inhibitory effect on melanogenesis or skin whitening | COLETICA (FR) | 1998-12-30 | — | — | EP | disclosed |