Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7516647 | 0.90 | ALDH1A1 (0.36) | ALDH1A1KDM4ETSHRL3MBTL1 | |
| SCHEMBL18023085 | 0.84 | ALDH1A1 (0.38) | ALDH1A1KDM4ETSHRL3MBTL1SMN1; SMN2 | |
| SCHEMBL18023105 | 0.84 | ALDH1A1 (0.38) | ALDH1A1KDM4ETSHRL3MBTL1SMN1; SMN2 | |
| SCHEMBL11444872 | 0.80 | ALDH1A1 (0.36) | ALDH1A1KDM4ETSHRL3MBTL1LMNA | |
| SCHEMBL128395 | 0.78 | LMNA (0.41) | ALDH1A1KDM4ETSHRL3MBTL1SMN1; SMN2 | |
| SCHEMBL25489245 | 0.77 | ALDH1A1 (0.37) | ALDH1A1KDM4ETSHRL3MBTL1SMN1; SMN2 | |
| SCHEMBL172789 | 0.77 | DNM1 (0.32) | — | |
| SCHEMBL2735121 | 0.76 | ALDH1A1 (0.41) | ALDH1A1KDM4ETSHRL3MBTL1SMN1; SMN2 | |
| SCHEMBL4609242 | 0.76 | ALDH1A1 (0.41) | ALDH1A1KDM4ETSHRL3MBTL1SMN1; SMN2 | |
| SCHEMBL20658227 | 0.75 | ALDH1A1 (0.33) | ALDH1A1KDM4ETSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1979331-B1 | TRISUBSTITUTED AMINE COMPOUNDS AS INHIBITORS OF -CHOLESTERYL ESTER TRANSFER PROTEIN CETP | MITSUBISHI TANABE PHARMA CORP (JP) | 2012-03-07 | — | — | EP | disclosed |