Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P4HB | P07237 | 5/20 | 0.55 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.55 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.55 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.55 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.55 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.55 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.55 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.55 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.54 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.53 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL47068 | 0.86 | ALDH1A1 (0.61) | P4HBGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL29677467 | 0.86 | ALDH1A1 (0.61) | P4HBGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL14604961 | 0.85 | P4HB (0.58) | P4HBGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL9277103 | 0.85 | P4HB (0.51) | P4HBGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL27302040 | 0.85 | P4HB (0.58) | P4HBGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL8367820 | 0.84 | LOXL2 (0.60) | P4HBGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL11456160 | 0.84 | P4HB (0.59) | P4HBGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL4407110 | 0.84 | P4HB (0.68) | P4HBGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL11222093 | 0.84 | P4HB (0.68) | P4HBGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL16618968 | 0.82 | P4HB (0.57) | P4HBGRIN2DGRIN3BGRIN1GRIN2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1179529-A1 | NOVEL HYDROXAMIC ACID DERIVATIVES | Daiichi Fine Chemical Co., Ltd. (JP) | 2002-02-13 | — | — | EP | disclosed |
| EP-1101492-A1 | NOVEL REMEDIES FOR ALLERGIC DISEASES | FUJI YAKUHIN KOGYO KABUSHIKI KAISHA (JP) | 2001-05-23 | — | — | EP | disclosed |
| EP-1038864-A1 | NOVEL METALLOPROTEINASE INHIBITORS | FUJI YAKUHIN KOGYO KABUSHIKI KAISHA (JP) | 2000-09-27 | — | — | EP | disclosed |