Iodomethane

Iodomethane

SCHEMBL7516696

CCN(CCCN(C)C)C(N)=O.CI

nearest known ligand 0.38

Full drug profile on Sugi Atlas →

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
CA12 O43570 2/20 0.38
CA1 P00915 2/20 0.38
CA9 Q16790 2/20 0.38
LMNA P02545 2/20 0.35
ALDH1A1 P00352 3/20 0.34
HRH4 Q9H3N8 2/20 0.34
CYP1A2 P05177 1/20 0.34
HRH2 P25021 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
USP2 O75604 1/20 0.34
DNM1 Q05193 4/20 0.33
HSD17B10 Q99714 1/20 0.33
TSHR P16473 1/20 0.33
KDM5A P29375 1/20 0.33
KDM5C P41229 1/20 0.33
KDM5D Q9BY66 1/20 0.33
KDM4C Q9H3R0 1/20 0.33
KDM5B Q9UGL1 1/20 0.33
PAOX Q6QHF9 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1531387 0.96 CA12 (0.41) CA12CA1CA9LMNAALDH1A1
Hydrochloric Acid SCHEMBL27811822 0.94 CA12 (0.39) CA12CA1CA9LMNAALDH1A1
SCHEMBL9129669 0.85 KDM5A (0.39) CA12CA1CA9LMNAALDH1A1
SCHEMBL35601 0.85 ALDH1A1 (0.41) LMNAALDH1A1HRH4CYP1A2HRH2
SCHEMBL18762850 0.81 ALDH1A1 (0.48) ALDH1A1HRH4CYP1A2HRH2TDP1
SCHEMBL293118 0.79 CA12 (0.59) CA12CA1CA9LMNAALDH1A1
SCHEMBL30620474 0.78 DNM1 (0.58) CA12CA1CA9ALDH1A1DNM1
SCHEMBL28916907 0.78 TDP1 (0.42) LMNAALDH1A1HRH4CYP1A2HRH2
SCHEMBL5197804 0.77 CA12 (0.52) CA12CA1CA9LMNAALDH1A1
SCHEMBL13185664 0.77 LMNA (0.47) CA12CA1CA9LMNAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1171136-A2 IMMUNOMODULATING COMPOSITION FOR USE ESPECIALLY IN THE TREATMENT OF INFLAMMATIONS, INFECTIONS AND SURGICAL ADHESIONS GENZYME CORPORATION (US) 2002-01-16 EP claimed
WO-2000059490-A2 IMMUNOMODULATING COMPOSITION FOR USE ESPECIALLY IN THE TREATMENT OF INFLAMMATIONS, INFECTIONS AND SURGICAL ADHESIONS GENZYME CORPORATION (US) 2000-10-12 WO claimed
EP-1171136-A2 IMMUNOMODULATING COMPOSITION FOR USE ESPECIALLY IN THE TREATMENT OF INFLAMMATIONS, INFECTIONS AND SURGICAL ADHESIONS GENZYME CORPORATION (US) 2002-01-16 EP disclosed
WO-2000059490-A2 IMMUNOMODULATING COMPOSITION FOR USE ESPECIALLY IN THE TREATMENT OF INFLAMMATIONS, INFECTIONS AND SURGICAL ADHESIONS GENZYME CORPORATION (US) 2000-10-12 WO disclosed