Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2B | P29275 | 7/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 5/20 | 0.37 |
| ▸ | PDE4A | P27815 | 3/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.35 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.35 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.35 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.35 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.35 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.35 |
| ▸ | GSK3A | P49840 | 2/20 | 0.33 |
| ▸ | GSK3B | P49841 | 2/20 | 0.33 |
| ▸ | LGMN | Q99538 | 1/20 | 0.33 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | GFER | P55789 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8456337 | 0.81 | GSK3B (0.41) | ADORA2BADORA2APDE4APDE4BPDE4C | |
| SCHEMBL12900999 | 0.74 | MAPT (0.38) | ADORA2BADORA2APDE4APDE4BPDE4C | |
| SCHEMBL19601231 | 0.70 | LGMN (0.47) | ADORA2BADORA2APDE4APDE4BPDE4C | |
| SCHEMBL2446004 | 0.69 | GSK3B (0.48) | ADORA2BADORA2APDE4APDE4BPDE4C | |
| SCHEMBL339514 | 0.69 | SIRT2 (0.33) | ADORA2BADORA2ASIRT2SIRT1SIRT3 | |
| SCHEMBL17595098 | 0.67 | LGMN (0.41) | ADORA2BADORA2APDE4APDE4BPDE4C | |
| SCHEMBL13492907 | 0.67 | ADORA2A (0.36) | ADORA2AKDM4EALDH1A1LMNAMAPT | |
| SCHEMBL10254094 | 0.65 | LGMN (0.33) | ADORA2BADORA2AGSK3AGSK3BLGMN | |
| SCHEMBL13904467 | 0.65 | ADORA2B (0.33) | ADORA2BADORA2AKDM4E | |
| SCHEMBL12660972 | 0.65 | F2 (0.40) | ADORA2BGSK3AGSK3BKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1080071-A4 | A PROCESS FOR PRODUCING AN ORGANIC TRISULFIDE COMPOUND | PHILLIPS PETROLEUM CO (US) | 2002-06-26 | — | — | EP | claimed |
| EP-1080071-A1 | A PROCESS FOR PRODUCING AN ORGANIC TRISULFIDE COMPOUND | Phillips Petroleum Company (US) | 2001-03-07 | — | — | EP | claimed |
| WO-1999059965-A1 | A PROCESS FOR PRODUCING AN ORGANIC TRISULFIDE COMPOUND | PHILLIPS PETROLEUM COMPANY (US) | 1999-11-25 | — | — | WO | claimed |
| EP-2922859-B1 | PHOSPHONUCLEOSIDES USEFUL IN THE TREATMENT OF VIRAL DISORDERS | UNIV CORK (IE) | 2021-05-05 | — | — | EP | disclosed |
| US-9822137-B2 | Phosphonucleosides useful in the treatment of viral disorders | UNIVERSITY COLLEGE CORK (IE) | 2017-11-21 | — | — | US | disclosed |
| US-20150291640-A1 | PHOSPHONUCLEOSIDES USEFUL IN THE TREATMENT OF VIRAL DISORDERS | KATHOLIEKE UNIVERSITEIT LEUVEN (BE) | 2015-10-15 | — | — | US | disclosed |
| EP-2922859-A1 | PHOSPHONUCLEOSIDES USEFUL IN THE TREATMENT OF VIRAL DISORDERS | University College Cork (IE) | 2015-09-30 | — | — | EP | disclosed |
| WO-2014079903-A1 | PHOSPHONUCLEOSIDES USEFUL IN THE TREATMENT OF VIRAL DISORDERS | UNIVERSITY COLLEGE CORK (IE) | 2014-05-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150291640-A1 | PHOSPHONUCLEOSIDES USEFUL IN THE TREATMENT OF VIRAL DISORDERS | ENTPD5, PNP, MTAP | ADORA2B 2122/4885ADORA2A 2042/4885PDE4A 588/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.