Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 5/20 | 0.48 |
| ▸ | DRD2 | P14416 | 4/20 | 0.48 |
| ▸ | DRD3 | P35462 | 2/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7463143 | 0.83 | ROCK1 (0.50) | — | |
| SCHEMBL7520899 | 0.83 | CHRNB2 (0.47) | DRD4DRD2DRD3ACHE | |
| SCHEMBL7518431 | 0.80 | ALDH1A1 (0.44) | — | |
| SCHEMBL7520395 | 0.79 | CHRNB2 (0.55) | ACHE | |
| SCHEMBL7521464 | 0.79 | ACHE (0.52) | DRD4DRD2ACHE | |
| SCHEMBL13450157 | 0.75 | ACHE (0.54) | ACHE | |
| SCHEMBL14159043 | 0.74 | ACHE (0.56) | ACHE | |
| SCHEMBL13450808 | 0.74 | ACHE (0.54) | DRD4DRD2ACHE | |
| SCHEMBL13462929 | 0.74 | DRD4 (0.53) | DRD4DRD2 | |
| SCHEMBL9131283 | 0.73 | DRD4 (0.66) | DRD4DRD2ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020151712-A1 | 3-pyrrolidinyloxy-3'-pyridyl ether compounds useful for controlling chemical synaptic transmission | LIN NAN-HORNG (US) | 2002-10-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020151712-A1 | 3-pyrrolidinyloxy-3'-pyridyl ether compounds useful for controlling chemical synaptic transmission | GAP43, SLC18A2, GABRE | DRD4 675/4885DRD2 391/4885DRD3 306/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.