Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.64 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 4/20 | 0.42 |
| ▸ | RAB9A | P51151 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | HPGD | P15428 | 4/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | APEX1 | P27695 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6966371 | 0.78 | SMN1; SMN2 (1.00) | SMN1; SMN2MEN1KMT2ACYP1A2CYP2C19 | |
| Water SCHEMBL11652814 | 0.77 | SMN1; SMN2 (0.96) | SMN1; SMN2MEN1KMT2ACYP1A2CYP2C19 | |
| SCHEMBL20037217 | 0.73 | MEN1 (0.60) | SMN1; SMN2MEN1KMT2ACYP1A2CYP2C19 | |
| SCHEMBL1800187 | 0.72 | SMN1; SMN2 (0.64) | SMN1; SMN2MEN1KMT2ACYP1A2CYP2C19 | |
| SCHEMBL1074115 | 0.70 | SMN1; SMN2 (0.60) | SMN1; SMN2MEN1KMT2ACYP1A2CYP2C19 | |
| SCHEMBL9871775 | 0.70 | MAPK1 (0.59) | MAPK1 | |
| SCHEMBL31706425 | 0.68 | HPGD (0.52) | SMN1; SMN2MEN1KMT2ACYP1A2HTT | |
| SCHEMBL4880757 | 0.68 | SMN1; SMN2 (0.57) | SMN1; SMN2MEN1KMT2ACYP1A2CYP2C19 | |
| SCHEMBL34059 | 0.67 | SMN1; SMN2 (0.72) | SMN1; SMN2MEN1KMT2ACYP1A2CYP2C19 | |
| SCHEMBL2453964 | 0.66 | SMN1; SMN2 (0.66) | SMN1; SMN2MEN1KMT2ACYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020050013-A1 | Composition for dyeing keratin fibers which contain at least one diaminopyrazole, dyeing process, novel diaminopyrazoles and process for their preparation | L'OREAL | 2002-05-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020050013-A1 | Composition for dyeing keratin fibers which contain at least one diaminopyrazole, dyeing process, novel diaminopyrazoles and process for their preparation | KRT18, DSP, TUBB3 | SMN1; SMN2 4233/4885MEN1 4103/4885KMT2A 1275/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.