SCHEMBL9871775

SCHEMBL9871775

CNc1nn(-c2ccccc2)c(C)cc1=O

nearest known ligand 0.59

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 1/20 0.59
RIPK1 Q13546 19/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9869941 0.84 RIPK1 (0.50) MAPK1RIPK1
SCHEMBL21904905 0.84 MAPK1 (0.64) MAPK1RIPK1
SCHEMBL9870358 0.83 MAPK1 (0.55) MAPK1RIPK1
SCHEMBL9870858 0.81 POLB (0.65)
SCHEMBL29773344 0.77 MAPK1 (0.54) MAPK1RIPK1
SCHEMBL3355960 0.74 MAPK1 (1.00) MAPK1RIPK1
SCHEMBL11388825 0.73 MAPK1 (0.74) MAPK1RIPK1
SCHEMBL29827072 0.72 MAPK1 (0.78) MAPK1RIPK1
SCHEMBL964125 0.71 MAPK1 (0.66) MAPK1
SCHEMBL7517044 0.70 SMN1; SMN2 (0.64) MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5059599-A Anxiolytic agents PIERRE FABRE MEDICAMENT (FR) 1991-10-22 US claimed