Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 18/20 | 0.69 |
| ▸ | CA4 | P22748 | 3/20 | 0.69 |
| ▸ | CA1 | P00915 | 3/20 | 0.63 |
| ▸ | CA12 | O43570 | 2/20 | 0.63 |
| ▸ | CA6 | P23280 | 2/20 | 0.63 |
| ▸ | CA5A | P35218 | 2/20 | 0.63 |
| ▸ | CA7 | P43166 | 2/20 | 0.63 |
| ▸ | CA9 | Q16790 | 2/20 | 0.63 |
| ▸ | CA13 | Q8N1Q1 | 2/20 | 0.63 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.63 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.63 |
| ▸ | LMNA | P02545 | 2/20 | 0.63 |
| ▸ | CA3 | P07451 | 1/20 | 0.39 |
| ▸ | AR | P10275 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7847722 | 1.00 | CA2 (0.69) | CA2CA4CA1CA12CA6 | |
| SCHEMBL3576264 | 0.94 | CA2 (0.79) | CA2CA4CA1CA12CA6 | |
| SCHEMBL2631258 | 0.94 | CA2 (0.79) | CA2CA4CA1CA12CA6 | |
| SCHEMBL3586580 | 0.94 | CA2 (0.79) | CA2CA4CA1CA12CA6 | |
| SCHEMBL8950315 | 0.85 | CA2 (0.64) | CA2CA4CA1CA12CA6 | |
| SCHEMBL8950300 | 0.84 | CA2 (0.50) | CA2CA4CA1CA12CA6 | |
| SCHEMBL9600441 | 0.84 | CA2 (0.70) | CA2CA4CA1CA12CA6 | |
| SCHEMBL7843136 | 0.84 | CA2 (0.47) | CA2CA4CA1CA12CA6 | |
| SCHEMBL7505749 | 0.83 | CA2 (0.89) | CA2CA4CA1CA12CA6 | |
| SCHEMBL7508613 | 0.83 | CA2 (0.89) | CA2CA4CA1CA12CA6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0527801-B1 | THIOPHENE SULFONAMIDES USEFUL AS CARBONIC ANHYDRASE INHIBITORS | ALCON LAB INC (US) | 2002-07-31 | — | — | EP | disclosed |
| WO-1993018016-A1 | FUNGICIDAL OXAZOLIDINONES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1993-09-16 | — | — | WO | disclosed |
| US-5240923-A | Treating glaucoma | ALCON LABORATORIES, INC. (US) | 1993-08-31 | — | — | US | disclosed |