Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 5/20 | 0.47 |
| ▸ | CA4 | P22748 | 2/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA6 | P23280 | 1/20 | 0.44 |
| ▸ | CA5A | P35218 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.44 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | GRIA1 | P42261 | 4/20 | 0.36 |
| ▸ | GRIA2 | P42262 | 4/20 | 0.36 |
| ▸ | GRIA3 | P42263 | 4/20 | 0.36 |
| ▸ | GRIA4 | P48058 | 4/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9260705 | 0.93 | CA2 (0.56) | CA2CA4CA12CA1CA6 | |
| SCHEMBL2726839 | 0.93 | CA2 (0.56) | CA2CA4CA12CA1CA6 | |
| SCHEMBL7846811 | 0.92 | CA2 (0.53) | CA2CA4CA12CA1CA6 | |
| SCHEMBL7517336 | 0.84 | CA2 (0.69) | CA2CA4CA12CA1CA6 | |
| SCHEMBL7847722 | 0.84 | CA2 (0.69) | CA2CA4CA12CA1CA6 | |
| SCHEMBL8950329 | 0.84 | CA2 (0.36) | CA2CA4CA12CA1CA6 | |
| SCHEMBL5617303 | 0.81 | CA2 (0.39) | CA2CA4CA12CA1CA6 | |
| SCHEMBL8950300 | 0.80 | CA2 (0.50) | CA2CA4CA12CA1CA6 | |
| SCHEMBL2631337 | 0.79 | CA2 (0.53) | CA2CA4CA12CA1CA6 | |
| SCHEMBL12603507 | 0.79 | CA2 (0.56) | CA2CA4CA12CA1CA6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0617038-B1 | Preparation of carbonic anhydrase inhibitors | ALCON LAB INC (US) | 2001-09-05 | — | — | EP | disclosed |
| US-5473067-A | Preparation of carbonic anhydrase inhibitors | ALCON LABORATORIES, INC. (US) | 1995-12-05 | — | — | US | disclosed |
| US-5424448-A | Preparation of carbonic anhydrase inhibitors | ALCON LABORATORIES, INC. (US) | 1995-06-13 | — | — | US | disclosed |
| EP-0617038-A1 | Preparation of carbonic anhydrase inhibitors | ALCON LABORATORIES, INC. (US) | 1994-09-28 | — | — | EP | disclosed |
| US-5344929-A | Preparation of carbonic anhydrase inhibitors | ALCON LABORATORIES, INC. (US) | 1994-09-06 | — | — | US | disclosed |