Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 10/20 | 0.50 |
| ▸ | CA4 | P22748 | 2/20 | 0.50 |
| ▸ | CA1 | P00915 | 2/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | CA6 | P23280 | 1/20 | 0.48 |
| ▸ | CA5A | P35218 | 1/20 | 0.48 |
| ▸ | CA7 | P43166 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.48 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.48 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8868900 | 0.93 | CA2 (0.57) | CA2CA4CA1CA12CA6 | |
| SCHEMBL8871391 | 0.93 | CA2 (0.57) | CA2CA4CA1CA12CA6 | |
| SCHEMBL8950080 | 0.89 | CA2 (0.41) | CA2CA4CA1CA12CA6 | |
| SCHEMBL8870138 | 0.86 | CA2 (0.46) | CA2CA4CA1CA12CA6 | |
| SCHEMBL7517336 | 0.84 | CA2 (0.69) | CA2CA4CA1CA12CA6 | |
| SCHEMBL7847722 | 0.84 | CA2 (0.69) | CA2CA4CA1CA12CA6 | |
| Hydrochloric Acid SCHEMBL9095308 | 0.82 | CA2 (0.43) | CA2CA4CA1CA12CA6 | |
| SCHEMBL8870509 | 0.81 | CA2 (0.37) | CA2CA4CA1CA12CA6 | |
| SCHEMBL7843136 | 0.80 | CA2 (0.47) | CA2CA4CA1CA12CA6 | |
| SCHEMBL2631258 | 0.78 | CA2 (0.79) | CA2CA4CA1CA12CA6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5538966-A | ENZYME INHIBITORS FOR TREATMENT OF GLAUCOMA | ALCON LABORATORIES, INC. (US) | 1996-07-23 | — | — | US | disclosed |