Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.41 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.39 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.39 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.39 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.38 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | ERN1 | O75460 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1080845 | 0.86 | TDP1 (0.44) | TDP1GPR35TSHRL3MBTL1CHRNB2 | |
| SCHEMBL14017372 | 0.86 | TDP1 (0.44) | TDP1GPR35TSHRL3MBTL1CHRNB2 | |
| SCHEMBL7214637 | 0.85 | CHRNB2 (0.41) | TDP1GPR35TSHRL3MBTL1TAS1R3 | |
| Hydrochloric Acid SCHEMBL7214642 | 0.85 | TDP1 (0.43) | TDP1GPR35TSHRL3MBTL1CHRNB2 | |
| Hydrochloric Acid SCHEMBL7214648 | 0.85 | TDP1 (0.43) | TDP1GPR35TSHRL3MBTL1CHRNB2 | |
| SCHEMBL1082453 | 0.84 | MAPT (0.48) | TDP1TSHRTAS1R3TAS1R1TAS1R2 | |
| SCHEMBL14651332 | 0.80 | HRH4 (0.46) | L3MBTL1ALDH1A1 | |
| SCHEMBL1573308 | 0.78 | TDP1 (0.38) | TDP1GPR35TSHRL3MBTL1TAS1R3 | |
| SCHEMBL12716705 | 0.78 | CHRNB2 (0.39) | TDP1GPR35TSHRL3MBTL1TAS1R3 | |
| SCHEMBL5916971 | 0.78 | GPR35 (0.46) | TDP1GPR35TSHRCHRNB2CHRNA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1017683-A4 | PROTECTING AND LINKING GROUPS FOR ORGANIC SYNTHESIS | ALCHEMIA PTY LTD (AU) | 2002-03-06 | — | — | EP | disclosed |
| EP-1017683-A1 | PROTECTING AND LINKING GROUPS FOR ORGANIC SYNTHESIS | Alchemia Pty. Ltd. (AU) | 2000-07-12 | — | — | EP | disclosed |
| EP-0977763-A4 | PROTECTED AMINOSUGARS | ALCHEMIA PTY LTD (AU) | 2000-07-12 | — | — | EP | disclosed |
| EP-0977763-A1 | PROTECTED AMINOSUGARS | Alchemia Pty. Ltd. (AU) | 2000-02-09 | — | — | EP | disclosed |
| WO-1999015510-A1 | PROTECTING AND LINKING GROUPS FOR ORGANIC SYNTHESIS | ALCHEMIA PTY. LTD. (AU) | 1999-04-01 | — | — | WO | disclosed |
| WO-1998038197-A1 | PROTECTED AMINOSUGARS | ALCHEMIA PTY. LTD. (AU) | 1998-09-03 | — | — | WO | disclosed |