Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO1 | P15559 | 1/20 | 0.41 |
| ▸ | APP | P05067 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | SCN4A | P35499 | 4/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5144061 | 0.86 | ALDH1A1 (0.44) | LMNATSHRTDP1 | |
| SCHEMBL9143121 | 0.82 | FFAR1 (0.50) | NQO1LMNATSHRMAPTFFAR1 | |
| SCHEMBL9143127 | 0.82 | FFAR1 (0.50) | NQO1LMNATSHRMAPTFFAR1 | |
| SCHEMBL4397519 | 0.79 | NQO1 (0.41) | NQO1APPLMNATSHRPOLB | |
| SCHEMBL18426854 | 0.79 | SCN4A (0.49) | NQO1APPSCN4A | |
| SCHEMBL16572200 | 0.79 | KDM4E (0.49) | NQO1APPTSHRMAPTTDP1 | |
| SCHEMBL10718066 | 0.79 | TDP1 (0.59) | NQO1APPTSHRMAPTTDP1 | |
| SCHEMBL7528014 | 0.78 | MAPT (0.47) | LMNATSHRPOLBMAPTNPSR1 | |
| SCHEMBL11068214 | 0.78 | LMNA (0.57) | LMNAMAPTSCN4A | |
| SCHEMBL14553340 | 0.76 | LTA4H (0.42) | NQO1APPTSHRMAPTCYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1054858-A1 | N-HYDROXY-2-(ALKYL, ARYL, OR HETEROARYL SULFANYL, SULFINYL OR SULFONYL)-3-SUBSTITUTED-ALKYL, ARYL OR HETEROARYLAMIDES AS MATRIX METALLOPROTEINASE INHIBITORS | American Cyanamid Company (US) | 2000-11-29 | — | — | EP | disclosed |
| WO-1999042436-A1 | N-HYDROXY-2-(ALKYL, ARYL, OR HETEROARYL SULFANYL, SULFINYL OR SULFONYL)-3-SUBSTITUTED-ALKYL, ARYL OR HETEROARYLAMIDES AS MATRIX METALLOPROTEINASE INHIBITORS | AMERICAN CYANAMID COMPANY (US) | 1999-08-26 | — | — | WO | disclosed |