Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | CETP | P11597 | 1/20 | 0.36 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7516002 | 0.88 | P2RY14 (0.39) | CETPRAB9AMAPTKMT2ARXFP1 | |
| SCHEMBL7512433 | 0.86 | POLB (0.41) | LMNANR1H4RAB9AMAPTNPC1 | |
| SCHEMBL7515762 | 0.86 | TP53 (0.41) | LMNAMAPTNPC1HPGDSMN1; SMN2 | |
| SCHEMBL7886119 | 0.78 | LOXL2 (0.46) | LMNACETPRAB9AMAPTNPC1 | |
| SCHEMBL7518226 | 0.73 | TSHR (0.48) | RAB9AMAPTNPC1ALDH1A1POLB | |
| SCHEMBL19953382 | 0.70 | NPC1 (0.51) | RAB9AMAPTNPC1SMN1; SMN2POLB | |
| SCHEMBL7520218 | 0.68 | KMT2A (0.56) | LMNARAB9ANPC1HPGDSMN1; SMN2 | |
| SCHEMBL12993470 | 0.66 | HSD17B10 (0.51) | LMNANR1H4HPGDSMN1; SMN2ALDH1A1 | |
| SCHEMBL4905164 | 0.66 | LOXL2 (0.55) | RAB9AMAPTNPC1SMN1; SMN2POLB | |
| SCHEMBL11337498 | 0.65 | NPC1 (0.47) | LMNARAB9AMAPTNPC1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1007518-A4 | SOLID AND LIQUID-PHASE SYNTHESIS OF BENZOXAZOLES AND BENZOTHIAZOLES AND THEIR USE | SEPRACOR INC (US) | 2002-11-06 | — | — | EP | disclosed |
| EP-1007518-A1 | SOLID AND LIQUID-PHASE SYNTHESIS OF BENZOXAZOLES AND BENZOTHIAZOLES AND THEIR USE | SEPRACOR, INC. (US) | 2000-06-14 | — | — | EP | disclosed |
| WO-1999009017-A1 | SOLID AND LIQUID-PHASE SYNTHESIS OF BENZOXAZOLES AND BENZOTHIAZOLES AND THEIR USE | SEPRACOR INC. (US) | 1999-02-25 | — | — | WO | disclosed |