Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.65 |
| ▸ | NPC1 | O15118 | 4/20 | 0.65 |
| ▸ | RAB9A | P51151 | 4/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.65 |
| ▸ | HPGD | P15428 | 2/20 | 0.65 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.65 |
| ▸ | LMNA | P02545 | 1/20 | 0.65 |
| ▸ | HTT | P42858 | 1/20 | 0.65 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.64 |
| ▸ | MAPT | P10636 | 4/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | CA12 | O43570 | 1/20 | 0.56 |
| ▸ | CA1 | P00915 | 1/20 | 0.56 |
| ▸ | CA2 | P00918 | 1/20 | 0.56 |
| ▸ | CA9 | Q16790 | 1/20 | 0.56 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.52 |
| ▸ | TUBB | P07437 | 1/20 | 0.52 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.52 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15223752 | 0.83 | KDM4E (0.65) | KDM4ENPC1RAB9AALDH1A1HPGD | |
| SCHEMBL1260807 | 0.81 | TUBB4A (0.72) | KDM4ENPC1RAB9AALDH1A1HPGD | |
| SCHEMBL22552071 | 0.80 | TUBB4A (0.77) | KDM4ENPC1RAB9AALDH1A1HPGD | |
| SCHEMBL29902976 | 0.80 | TUBB4A (0.77) | KDM4ENPC1RAB9AALDH1A1HPGD | |
| SCHEMBL5788655 | 0.80 | TUBB4A (0.51) | KDM4ENPC1RAB9AALDH1A1HPGD | |
| SCHEMBL12392692 | 0.80 | KDM4E (0.60) | KDM4ENPC1RAB9AALDH1A1HPGD | |
| SCHEMBL4264688 | 0.80 | KDM4E (0.81) | KDM4ENPC1RAB9AALDH1A1HPGD | |
| SCHEMBL75327 | 0.79 | KDM4E (1.00) | KDM4ENPC1RAB9AALDH1A1HPGD | |
| SCHEMBL15058692 | 0.79 | KDM4E (0.74) | KDM4ENPC1RAB9AALDH1A1HPGD | |
| SCHEMBL7848024 | 0.79 | HRH3 (0.55) | KDM4ENPC1RAB9AALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1165512-A2 | METHOD FOR ARYLATING AZA-HETEROCYCLES WITH ACTIVATED AROMATIC COMPOUNDS IN THE PRESENCE OF CESIUM CARBONATE | GÖDECKE GMBH (DE) | 2002-01-02 | — | — | EP | disclosed |
| WO-2000059883-A2 | METHOD FOR PRODUCING N-ARYL-AZA-HETEROCYCLES IN THE PRESENCE OF CESIUM CARBONATE | Gödecke GmbH (DE) | 2000-10-12 | — | — | WO | disclosed |