SCHEMBL7518283

SCHEMBL7518283

C=C(C)C(=O)OOC(C)SC(C)(OOC(=O)C(=C)C)c1ccccc1

nearest known ligand 0.33

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ELANE P08246 1/20 0.33
ALDH1A1 P00352 2/20 0.31
TDP1 Q9NUW8 2/20 0.31
TSHR P16473 1/20 0.31
HSD17B10 Q99714 1/20 0.31
CYP1A2 P05177 1/20 0.31
CYP2D6 P10635 1/20 0.31
MAPT P10636 1/20 0.30
KMT2A Q03164 1/20 0.30
MAPK1 P28482 1/20 0.30
KIF11 P52732 1/20 0.30
KDM4E B2RXH2 1/20 0.30
NPSR1 Q6W5P4 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16016805 0.74 MAPK1 (0.53) ELANEALDH1A1TDP1TSHRHSD17B10
SCHEMBL7515050 0.74 ELANE (0.39) ELANEALDH1A1MAPTKMT2AKDM4E
SCHEMBL8681581 0.68 ELANE (0.36) ELANEALDH1A1TDP1TSHRHSD17B10
SCHEMBL16817793 0.67 CYP1A2 (0.42) ELANEALDH1A1TDP1TSHRCYP1A2
SCHEMBL3180129 0.66 CYP2C19 (0.46) ELANEALDH1A1TDP1CYP1A2CYP2D6
SCHEMBL8639922 0.66 ELANE (0.37) ELANEALDH1A1TDP1CYP1A2CYP2D6
Hydrochloric Acid SCHEMBL166562 0.65 ELANE (0.36) ELANEALDH1A1TDP1CYP1A2CYP2D6
SCHEMBL3393201 0.65 ALDH1A1 (0.48) ELANEALDH1A1TDP1CYP1A2CYP2D6
SCHEMBL27612149 0.64 HIF1A (0.41) ELANEALDH1A1TDP1TSHRCYP1A2
SCHEMBL27861873 0.64 MAPK1 (0.57) ELANEALDH1A1TDP1TSHRHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0735062-B1 ACTINIC-RADIATION-CURABLE COMPOSITION AND LENS SHEET MITSUBISHI RAYON CO (JP) 2002-01-30 EP claimed
US-6206550-B1 BACKLIGHT WITH LENS PORTION MADE FROM A CURABLE COMPOSITION WHICH INCLUDES A BIS(4-(METH)ACRYLOYL-THIOPHENYL) SULFIDE AND (METH)ACRYLATES; HIGH BRIGHTNESS-ENHANCING EFFECT ON LENSES OF PROJECTION TVS AND STEREOSCOPIC PHOTOGRAPHY. MITSUBISHI RAYON COMPANY LTD. (JP) 2001-03-27 US claimed
US-5969867-A ACRYLIC ESTERS MITSUBISHI RAYON COMPANY LTD. (JP) 1999-10-19 US claimed
EP-0735062-A1 ACTINIC-RADIATION-CURABLE COMPOSITION AND LENS SHEET MITSUBISHI RAYON CO., LTD. (JP) 1996-10-02 EP claimed