Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 known ✓ | O15379 | 1/20 | 0.35 |
| ▸ | HDAC4 known ✓ | P56524 | 1/20 | 0.35 |
| ▸ | HDAC1 known ✓ | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC7 known ✓ | Q8WUI4 | 1/20 | 0.35 |
| ▸ | HDAC2 known ✓ | Q92769 | 1/20 | 0.35 |
| ▸ | HDAC10 known ✓ | Q969S8 | 1/20 | 0.35 |
| ▸ | HDAC11 known ✓ | Q96DB2 | 1/20 | 0.35 |
| ▸ | HDAC8 known ✓ | Q9BY41 | 1/20 | 0.35 |
| ▸ | HDAC6 known ✓ | Q9UBN7 | 1/20 | 0.35 |
| ▸ | HDAC9 known ✓ | Q9UKV0 | 1/20 | 0.35 |
| ▸ | HDAC5 known ✓ | Q9UQL6 | 1/20 | 0.35 |
| ▸ | GAA known ✓ | P10253 | 2/20 | 0.33 |
| ▸ | GLA known ✓ | P06280 | 1/20 | 0.33 |
| ▸ | KCNH2 known ✓ | Q12809 | 1/20 | 0.33 |
| ▸ | ELANE | P08246 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8639922 | 0.99 | ELANE (0.37) | ELANEMAPTKCNN4HDAC3HDAC4 | |
| Hydrochloric Acid SCHEMBL3899766 | 0.83 | MAPT (0.37) | ELANEMAPTKCNN4KDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL29259117 | 0.82 | TDP1 (0.33) | ELANEALDH1A1TDP1 | |
| Hydrochloric Acid SCHEMBL2794371 | 0.80 | MAPT (0.36) | MAPTKCNN4HDAC3HDAC4HDAC1 | |
| SCHEMBL11572068 | 0.78 | KCNN4 (0.37) | MAPTKCNN4HDAC3HDAC4HDAC1 | |
| SCHEMBL26305 | 0.74 | ALDH1A1 (0.43) | ALDH1A1 | |
| SCHEMBL305727 | 0.74 | ALDH1A1 (0.45) | ELANEMAPTHDAC3HDAC4HDAC1 | |
| SCHEMBL28086564 | 0.74 | ELANE (0.41) | ELANEMAPTKCNN4HDAC3HDAC4 | |
| Methacrylic Acid SCHEMBL21611350 | 0.73 | ALDH1A1 (0.39) | ALDH1A1 | |
| SCHEMBL3447565 | 0.73 | ALDH1A1 (0.39) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 172 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120082002-A | Low-surface-energy antibacterial resin material, preparation method and marine antifouling paint | 中国人民武装警察部队士官学校 | 2025-06-03 | — | — | CN | claimed |
| CN-120059264-A | Universal functional coating material and preparation method thereof | 陕西师范大学 | 2025-05-30 | — | — | CN | claimed |
| CN-119980753-A | Papermaking method for improving paper strength | 瑞辰星生物技术（广州）有限公司 | 2025-05-13 | — | — | CN | claimed |
| CN-119980752-A | Papermaking method for improving paper strength | 瑞辰星生物技术（广州）有限公司 | 2025-05-13 | — | — | CN | claimed |
| CN-119529175-A | Polyacrylamide aqueous dispersion, and synthetic method and application thereof | 中国石油化工股份有限公司 | 2025-02-28 | — | — | CN | claimed |
| CN-119529176-A | Polyacrylamide aqueous dispersion, and synthetic method and application thereof | 中国石油化工股份有限公司 | 2025-02-28 | — | — | CN | claimed |
| CN-119529807-A | Salt-resistant anti-swelling slick water and application thereof | 中国石油化工股份有限公司 | 2025-02-28 | — | — | CN | claimed |
| CN-119433978-A | Composite material non-woven fabric and preparation method thereof | 山东恒塔环保科技有限公司 | 2025-02-14 | — | — | CN | claimed |
| CN-119409907-A | Method for producing polyacrylamide by kneader | 江苏派克斯特纤维素有限公司 | 2025-02-11 | — | — | CN | claimed |
| CN-118558161-B | Polyamide composite membrane based on positively charged supporting layer and preparation method and application thereof | 浙江大学 | 2024-12-27 | — | — | CN | claimed |
| CN-113150212-A | Preparation method of efficient waterproof agent for paper | 杭州绿邦科技有限公司 | 2021-07-23 | — | — | CN | claimed |
| CN-107601820-B | Preparation method of cationic polyacrylamide sludge dehydrating agent | 重庆大学 | 2020-11-24 | — | — | CN | claimed |
| CN-107936173-B | Hydrophobic association type cationic polyacrylamide and preparation method and application thereof | 陕西科技大学 | 2020-10-23 | — | — | CN | claimed |
| US-10704201-B2 | Dry strength agent composition and method for enhancing the dry strength of paper | ECOLAB USA INC. (US) | 2020-07-07 | — | — | US | claimed |
| US-10668157-B2 | Anionic drug-containing medical device | SEED CO., LTD. (JP) | 2020-06-02 | — | — | US | claimed |
| US-20180320316-A1 | DRY STRENGTH AGENT COMPOSITION AND METHOD FOR ENHANCING THE DRY STRENGTH OF PAPER | ECOLAB USA INC. (US) | 2018-11-08 | — | — | US | claimed |
| EP-3397811-A1 | DRY STRENGTH AGENT COMPOSITION AND METHOD FOR ENHANCING THE DRY STRENGTH OF PAPER | Ecolab USA, Inc. (US) | 2018-11-07 | — | — | EP | claimed |
| US-20140050995-A1 | METAL-FREE OXYGEN REDUCTION ELECTROCATALYSTS | NATIONAL SCIENCE FOUNDATION | 2014-02-20 | — | — | US | claimed |
| WO-2012118948-A1 | METAL-FREE OXYGEN REDUCTION ELECTROCATALYSTS | CASE WESTERN RESERVE UNIVERSITY (US) | 2012-09-07 | — | — | WO | claimed |
| US-20110210064-A1 | FILTRATION MATERIAL FOR DESALINATION | INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) | 2011-09-01 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10668157-B2 | Anionic drug-containing medical device | ACMSD, ADSL, AAAS | HDAC3 2987/4885HDAC4 3314/4885HDAC1 2196/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.