Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | ZDHHC20 | Q5W0Z9 | 3/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.34 |
| ▸ | ELANE | P08246 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7522251 | 0.81 | DPP4 (0.40) | DPP4ZDHHC20ZDHHC2ELANECYP1A2 | |
| SCHEMBL7524699 | 0.76 | DPP4 (0.50) | DPP4MEN1KMT2AALDH1A1TSHR | |
| SCHEMBL7524652 | 0.75 | ALDH1A1 (0.40) | DPP4MEN1KMT2AALDH1A1TSHR | |
| SCHEMBL10957529 | 0.73 | DPP4 (0.43) | DPP4MEN1KMT2AALDH1A1TSHR | |
| SCHEMBL11453591 | 0.72 | ALDH1A1 (0.38) | MEN1KMT2AALDH1A1TSHRCYP2C9 | |
| SCHEMBL7523722 | 0.71 | ALDH1A1 (0.34) | DPP4MEN1KMT2AALDH1A1TSHR | |
| SCHEMBL9315853 | 0.70 | ACHE (0.37) | MEN1KMT2AALDH1A1TSHRLMNA | |
| SCHEMBL9316395 | 0.69 | ALDH1A1 (0.35) | ALDH1A1CYP2C9LMNAHSD17B10L3MBTL1 | |
| SCHEMBL7314381 | 0.69 | ALDH1A1 (0.33) | ALDH1A1CYP2C9LMNAHSD17B10ALOX15 | |
| SCHEMBL9404507 | 0.69 | GAA (0.41) | KMT2AALDH1A1LMNACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0816342-B1 | Process for producing 1-substituted-hydantoins | SUMITOMO CHEMICAL CO (JP) | 2002-02-27 | — | — | EP | disclosed |
| US-5883260-A | Process for producing 1-substituted-hydantoins | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1999-03-16 | — | — | US | disclosed |
| EP-0816342-A2 | Process for producing 1-substituted-hydantoins | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1998-01-07 | — | — | EP | disclosed |