Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | DPP4 | P27487 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7524527 | 0.83 | DPP4 (0.34) | DPP4 | |
| SCHEMBL7518459 | 0.71 | DPP4 (0.39) | ALDH1A1LMNAHSD17B10L3MBTL1MEN1 | |
| SCHEMBL10957529 | 0.70 | DPP4 (0.43) | ALDH1A1LMNAHSD17B10L3MBTL1MEN1 | |
| SCHEMBL8566391 | 0.68 | CTSS (0.37) | LMNAMEN1KMT2ADPP4CYP2C9 | |
| SCHEMBL20306165 | 0.65 | ALDH1A1 (0.42) | ALDH1A1LMNAPOLBHSD17B10L3MBTL1 | |
| SCHEMBL11351147 | 0.65 | MEN1 (0.44) | ALDH1A1LMNAHSD17B10L3MBTL1MEN1 | |
| Formic Acid SCHEMBL6611494 | 0.65 | DPP4 (0.35) | ALDH1A1DPP4 | |
| SCHEMBL8961040 | 0.64 | ALDH1A1 (0.36) | ALDH1A1LMNAPOLBHSD17B10L3MBTL1 | |
| SCHEMBL3298428 | 0.63 | DPP4 (0.37) | MEN1KMT2ADPP4HTT | |
| SCHEMBL22762835 | 0.63 | HDAC6 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0816342-B1 | Process for producing 1-substituted-hydantoins | SUMITOMO CHEMICAL CO (JP) | 2002-02-27 | — | — | EP | disclosed |
| US-5883260-A | Process for producing 1-substituted-hydantoins | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1999-03-16 | — | — | US | disclosed |
| EP-0816342-A2 | Process for producing 1-substituted-hydantoins | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1998-01-07 | — | — | EP | disclosed |