Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.33 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.33 |
| ▸ | NQO1 | P15559 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 6/20 | 0.32 |
| ▸ | ESR2 | Q92731 | 6/20 | 0.32 |
| ▸ | MAOB | P27338 | 2/20 | 0.32 |
| ▸ | HTR1D | P28221 | 1/20 | 0.32 |
| ▸ | HTR1B | P28222 | 1/20 | 0.32 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.31 |
| ▸ | AR | P10275 | 1/20 | 0.31 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4966941 | 0.84 | TRPA1 (0.35) | TRPA1MAOAPTGS1ESR1ESR2 | |
| SCHEMBL11786591 | 0.82 | CYP3A4 (0.40) | MCL1MAOBTDP1CSNK2A1 | |
| SCHEMBL13264060 | 0.81 | ESR1 (0.36) | TRPA1ESR1ESR2 | |
| SCHEMBL16334848 | 0.81 | ERN1 (0.32) | MAOAPTGS1MAOBCSNK2A1 | |
| SCHEMBL7514297 | 0.81 | SCN5A (0.33) | TRPA1ATMMAOAPTGS1NQO1 | |
| SCHEMBL6591933 | 0.80 | SRD5A1 (0.47) | TRPA1ATMPTGS1SRD5A1ESR1 | |
| SCHEMBL7519840 | 0.79 | HIF1A (0.36) | TRPA1ATMMAOAPTGS1NQO1 | |
| SCHEMBL8827947 | 0.76 | ESR1 (0.43) | TRPA1ATMNQO1ESR1ESR2 | |
| SCHEMBL5954018 | 0.76 | TRPA1 (0.45) | TRPA1ATMTP53 | |
| SCHEMBL4878065 | 0.74 | TRPA1 (0.41) | TRPA1ATMNQO1ESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0784528-B1 | ABRASIVE ARTICLES WITH ENCAPSULATED LUBRICANT | MINNESOTA MINING & MFG (US) | 2002-01-30 | — | — | EP | claimed |
| US-5725617-A | Abrasive articles with encapsulated lubricant | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1998-03-10 | — | — | US | claimed |
| EP-0784528-A1 | ABRASIVE ARTICLES WITH ENCAPSULATED LUBRICANT | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1997-07-23 | — | — | EP | claimed |
| WO-1996011085-A1 | ABRASIVE ARTICLES WITH ENCAPSULATED LUBRICANT | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1996-04-18 | — | — | WO | claimed |
| EP-0784528-B1 | ABRASIVE ARTICLES WITH ENCAPSULATED LUBRICANT | MINNESOTA MINING & MFG (US) | 2002-01-30 | — | — | EP | disclosed |
| US-5725617-A | Abrasive articles with encapsulated lubricant | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1998-03-10 | — | — | US | disclosed |
| EP-0784528-A1 | ABRASIVE ARTICLES WITH ENCAPSULATED LUBRICANT | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1997-07-23 | — | — | EP | disclosed |
| WO-1996011085-A1 | ABRASIVE ARTICLES WITH ENCAPSULATED LUBRICANT | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1996-04-18 | — | — | WO | disclosed |