SCHEMBL7518593

SCHEMBL7518593

CS(=O)(=O)N(Cc1ccccc1)c1cccc([C@@H](O)CNCc2ccccc2)c1

nearest known ligand 0.54

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
ADRB3 P13945 2/20 0.54
SLC16A3 O15427 1/20 0.48
LMNA P02545 4/20 0.47
MEN1 O00255 2/20 0.47
KMT2A Q03164 2/20 0.47
GRM2 Q14416 2/20 0.45
POLB P06746 2/20 0.44
ALDH1A1 P00352 2/20 0.42
PLA2G1B P04054 1/20 0.42
ATG4B Q9Y4P1 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7513335 1.00 ADRB3 (0.54) ADRB3SLC16A3LMNAMEN1KMT2A
SCHEMBL27557792 0.89 GRM2 (0.46) ADRB3LMNAMEN1KMT2AGRM2
SCHEMBL7251978 0.83 LMNA (0.50) LMNAMEN1KMT2AGRM2POLB
SCHEMBL7528794 0.83 LMNA (0.50) LMNAMEN1KMT2AGRM2POLB
SCHEMBL7526398 0.83 GRM2 (0.51) LMNAMEN1KMT2AGRM2POLB
SCHEMBL7244999 0.82 GRM2 (0.47) LMNAMEN1KMT2AGRM2POLB
SCHEMBL7623436 0.78 GRM2 (0.44) LMNAMEN1KMT2AGRM2POLB
SCHEMBL7530130 0.78 GRM2 (0.44) LMNAMEN1KMT2AGRM2POLB
SCHEMBL5194363 0.78 GRM2 (0.44) LMNAMEN1KMT2AGRM2POLB
SCHEMBL5196623 0.78 GRM2 (0.44) LMNAMEN1KMT2AGRM2POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1174426-A1 METHOD FOR THE PREPARATION OF TRICYCLIC AMINO ALCOHOL DERIVATIVES THROUGH AZIDES Asahi Kasei Kabushiki Kaisha (JP) 2002-01-23 EP disclosed