Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.41 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7528794 | 0.88 | LMNA (0.50) | GRM2LMNAPOLBALDH1A1MEN1 | |
| SCHEMBL7251978 | 0.88 | LMNA (0.50) | GRM2LMNAPOLBALDH1A1MEN1 | |
| SCHEMBL7244999 | 0.86 | GRM2 (0.47) | GRM2LMNAPOLBALDH1A1MEN1 | |
| SCHEMBL7513335 | 0.83 | ADRB3 (0.54) | GRM2LMNAPOLBALDH1A1MEN1 | |
| SCHEMBL7518593 | 0.83 | ADRB3 (0.54) | GRM2LMNAPOLBALDH1A1MEN1 | |
| SCHEMBL7530130 | 0.82 | GRM2 (0.44) | GRM2LMNAPOLBALDH1A1MEN1 | |
| SCHEMBL5194363 | 0.82 | GRM2 (0.44) | GRM2LMNAPOLBALDH1A1MEN1 | |
| SCHEMBL7623436 | 0.82 | GRM2 (0.44) | GRM2LMNAPOLBALDH1A1MEN1 | |
| SCHEMBL5196623 | 0.82 | GRM2 (0.44) | GRM2LMNAPOLBALDH1A1MEN1 | |
| SCHEMBL27557792 | 0.82 | GRM2 (0.46) | GRM2LMNAPOLBALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1174426-A1 | METHOD FOR THE PREPARATION OF TRICYCLIC AMINO ALCOHOL DERIVATIVES THROUGH AZIDES | Asahi Kasei Kabushiki Kaisha (JP) | 2002-01-23 | — | — | EP | disclosed |