Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCI | P41743 | 14/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | PTPN12 | Q05209 | 1/20 | 0.39 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5802431 | 0.95 | PRKCI (0.47) | PRKCIALDH1A1HTTSMN1; SMN2PRKCZ | |
| SCHEMBL5798171 | 0.87 | MEN1 (0.46) | PRKCIALDH1A1HTTSMN1; SMN2PTPN12 | |
| SCHEMBL7533225 | 0.84 | ALDH1A1 (0.47) | PRKCIALDH1A1HTTSMN1; SMN2PTPN12 | |
| SCHEMBL5816198 | 0.84 | FAAH (0.38) | ALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL7518212 | 0.83 | FAAH (0.38) | — | |
| SCHEMBL5779219 | 0.82 | HTT (0.48) | PRKCIALDH1A1HTTSMN1; SMN2PTPN12 | |
| SCHEMBL5119049 | 0.82 | PDE5A (0.39) | ALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL5800724 | 0.82 | MEN1 (0.46) | PRKCIHTTSMN1; SMN2 | |
| SCHEMBL5780867 | 0.82 | PRKCI (0.66) | PRKCIPRKCZ | |
| SCHEMBL5800802 | 0.81 | PRKCI (0.52) | PRKCIALDH1A1HTTSMN1; SMN2PRKCZ |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0920431-A1 | THIENOPYRIMIDINES | MERCK PATENT GmbH (DE) | 1999-06-09 | — | — | EP | disclosed |
| WO-1998006722-A1 | THIENOPYRIMIDINES | MERCK PATENT GMBH (DE) | 1998-02-19 | — | — | WO | disclosed |