Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.34 |
| ▸ | DRD4 | P21917 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
| ▸ | DRD3 | P35462 | 1/20 | 0.34 |
| ▸ | HTR2B | P41595 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.33 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7513508 | 0.76 | ALDH1A1 (0.35) | DRD2MEN1KMT2AHTR1AADRA2A | |
| SCHEMBL7576603 | 0.76 | ALDH1A1 (0.37) | MEN1KMT2AALDH1A1SMN1; SMN2CA1 | |
| SCHEMBL25756589 | 0.69 | CYP1B1 (0.46) | ALDH1A1SMN1; SMN2CHRM5MAPTCYP1B1 | |
| SCHEMBL7584565 | 0.65 | ALDH1A1 (0.41) | MEN1KMT2AALDH1A1SMN1; SMN2CA1 | |
| SCHEMBL4535876 | 0.65 | MAPT (0.38) | MEN1KMT2AALDH1A1SMN1; SMN2USP2 | |
| SCHEMBL5059322 | 0.65 | TDP2 (0.40) | MEN1KMT2AALDH1A1SMN1; SMN2USP2 | |
| SCHEMBL25756590 | 0.59 | KMT2A (0.34) | DRD2MEN1KMT2AHTR1AADRA2A | |
| SCHEMBL4386782 | 0.58 | ALDH1A1 (0.40) | MEN1KMT2AALDH1A1USP2MAPT | |
| SCHEMBL20478946 | 0.56 | KMT2A (0.47) | MEN1KMT2AALDH1A1SMN1; SMN2CA1 | |
| SCHEMBL25171514 | 0.56 | KDM4E (0.67) | MEN1KMT2AALDH1A1USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1226146-A2 | QUINOLINE AND NAPHTHYRIDINE CARBOXYLIC ACID ANTIBACTERIALS | ABBOTT LABORATORIES (US) | 2002-07-31 | — | — | EP | disclosed |
| WO-2001032655-A2 | QUINOLINE AND NAPHTHYRIDINE CARBOXYLIC ACID ANTIBACTERIALS | ABBOTT LABORATORIES (US) | 2001-05-10 | — | — | WO | disclosed |