SCHEMBL751960

SCHEMBL751960

CC(CC(C)S(=O)(=O)O)OC(C)CC(C)S(=O)(=O)O

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 1/20 0.32
TP53 P04637 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14955405 0.81 TP53 (0.37) TP53
SCHEMBL6720279 0.76 SLC7A5 (0.40) MAPK1TP53
SCHEMBL11872650 0.74 TSHR (0.33) TP53
SCHEMBL6687959 0.74 TP53 (0.33) TP53
Hydrochloric Acid SCHEMBL27819023 0.74 SLC7A5 (0.39) MAPK1TP53
SCHEMBL11367356 0.72 TP53 (0.32) TP53
SCHEMBL19034720 0.72 TP53 (0.32) TP53
SCHEMBL10028834 0.72 TP53 (0.32) TP53
SCHEMBL1766368 0.72 TP53 (0.32) TP53
SCHEMBL1919161 0.71 TP53 (0.33) TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3100728-B1 PHARMACEUTICAL COMPOSITIONS COMPRISING PRASUGREL AND CYCLODEXTRIN DERIVATIVES AND METHODS OF MAKING AND USING THE SAME CYDEX PHARMACEUTICALS INC (US) 2019-11-20 EP disclosed
US-10111863-B2 Pharmaceutical compositions comprising prasugrel and cyclodextrin derivatives and methods of making and using the same CYDEX PHARMACEUTICALS, INC. (US) 2018-10-30 US disclosed
US-20170007586-A1 PHARMACEUTICAL COMPOSITIONS COMPRISING PRASUGREL AND CYCLODEXTRIN DERIVATIVES AND METHODS OF MAKING AND USING THE SAME CITIBANK, N.A., AS ADMINISTRATIVE AGENT 2017-01-12 US disclosed
EP-3100728-A1 PHARMACEUTICAL COMPOSITIONS COMPRISING PRASUGREL AND CYCLODEXTRIN DERIVATIVES AND METHODS OF MAKING AND USING THE SAME Cydex Pharmaceuticals, Inc. (US) 2016-12-07 EP disclosed
US-9399067-B2 Pharmaceutical compositions comprising prasugrel and cyclodextrin derivatives and methods of making and using the same CYDEX PHARMACEUTICALS, INC. (US) 2016-07-26 US disclosed
EP-2429291-B1 PHARMACEUTICAL COMPOSITIONS COMPRISING PRASUGREL AND CYCLODEXTRIN DERIVATIVES AND METHODS OF MAKING AND USING THE SAME CYDEX PHARMACEUTICALS INC (US) 2016-07-06 EP disclosed
US-9240614-B2 Nonaqueous electrolyte solution and electrochemical element using same UBE INDUSTRIES, LTD. (JP) 2016-01-19 US disclosed
US-20150005341-A1 PHARMACEUTICAL COMPOSITIONS COMPRISING PRASUGREL AND CYCLODEXTRIN DERIVATIVES AND METHODS OF MAKING AND USING THE SAME CITIBANK, N.A., AS ADMINISTRATIVE AGENT 2015-01-01 US disclosed
US-8835407-B2 Pharmaceutical compositions comprising prasugrel and cyclodextrin derivatives and methods of making and using the same CYDEX PHARMACEUTICALS, INC. (US) 2014-09-16 US disclosed
EP-2579377-B1 NONAQUEOUS ELECTROLYTE SOLUTION AND ELECTROCHEMICAL ELEMENT USING SAME UBE INDUSTRIES (JP) 2014-09-03 EP disclosed
EP-2579377-A1 NONAQUEOUS ELECTROLYTE SOLUTION AND ELECTROCHEMICAL ELEMENT USING SAME Ube Industries, Ltd. (JP) 2013-04-10 EP disclosed
US-20130071733-A1 NONAQUEOUS ELECTROLYTE SOLUTION AND ELECTROCHEMICAL ELEMENT USING SAME UBE INDUSTRIES, LTD. (JP) 2013-03-21 US disclosed
US-20130012534-A1 Pharmaceutical Compositions Comprising Prasugrel and Cyclodextrin Derivatives and Methods of Making and Using the Same CYDEX PHARMACEUTICALS, INC. 2013-01-10 US disclosed
US-8236782-B2 Pharmaceutical compositions comprising prasugrel and cyclodextrin derivatives and methods of making and using the same CYDEX PHARMACEUTICALS, INC. (US) 2012-08-07 US disclosed
EP-2429291-A1 PHARMACEUTICAL COMPOSITIONS COMPRISING PRASUGREL AND CYCLODEXTRIN DERIVATIVES AND METHODS OF MAKING AND USING THE SAME CyDex Pharmaceuticals, Inc. (US) 2012-03-21 EP disclosed
WO-2010132711-A1 PHARMACEUTICAL COMPOSITIONS COMPRISING PRASUGREL AND CYCLODEXTRIN DERIVATIVES AND METHODS OF MAKING AND USING THE SAME CYDEX PHARMACEUTICALS, INC. (US) 2010-11-18 WO disclosed
US-20100291056-A1 Pharmaceutical Compositions Comprising Prasugrel and Cyclodextrin Derivatives and Methods of Making and Using the Same CITIBANK, N.A., AS ADMINISTRATIVE AGENT 2010-11-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170007586-A1 PHARMACEUTICAL COMPOSITIONS COMPRISING PRASUGREL AND CYCLODEXTRIN DERIVATIVES AND METHODS OF MAKING AND USING THE SAME P2RY6, GP6, PFKP MAPK1 4127/4885TP53 2392/4885
US-20150005341-A1 PHARMACEUTICAL COMPOSITIONS COMPRISING PRASUGREL AND CYCLODEXTRIN DERIVATIVES AND METHODS OF MAKING AND USING THE SAME P2RY6, GP6, PFKP MAPK1 4127/4885TP53 2392/4885
US-20130012534-A1 Pharmaceutical Compositions Comprising Prasugrel and Cyclodextrin Derivatives and Methods of Making and Using the Same P2RY6, GP6, PFKP MAPK1 4127/4885TP53 2392/4885
US-10111863-B2 Pharmaceutical compositions comprising prasugrel and cyclodextrin derivatives and methods of making and using the same P2RY6, GP6, PFKP MAPK1 4127/4885TP53 2392/4885
US-20100291056-A1 Pharmaceutical Compositions Comprising Prasugrel and Cyclodextrin Derivatives and Methods of Making and Using the Same P2RY6, GP6, PFKP MAPK1 4127/4885TP53 2392/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.