SCHEMBL7519611

SCHEMBL7519611

Nc1ccc(-c2cccc3c2C(c2ccc(N)cc2)c2ccccc2C3)cc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 9/20 0.40
KDM4E B2RXH2 1/20 0.39
NPC1 O15118 1/20 0.39
ALDH1A1 P00352 1/20 0.39
LMNA P02545 1/20 0.39
MAPT P10636 1/20 0.39
HPGD P15428 1/20 0.39
RAB9A P51151 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
HRH1 P35367 3/20 0.37
HTR2C P28335 2/20 0.37
KIT P10721 2/20 0.34
KDR P35968 2/20 0.34
FLT3 P36888 2/20 0.34
HTR6 P50406 3/20 0.33
CHRNB2 P17787 1/20 0.33
CHRNA4 P43681 1/20 0.33
NCOA1 Q15788 1/20 0.33
NCOA3 Q9Y6Q9 1/20 0.33
SLC6A2 P23975 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22418784 0.86 HTR2A (0.43) HTR2AALDH1A1LMNAMAPTHPGD
SCHEMBL28546468 0.83 HTR2A (0.38) HTR2ALMNAMAPTHPGDHRH1
SCHEMBL1034459 0.80 HSD17B10 (0.38) HTR2AALDH1A1KITKDRFLT3
SCHEMBL2125513 0.78 GSTP1 (0.37) HTR2AKDM4EHRH1HTR2CSLC6A2
SCHEMBL28547777 0.76 HDAC4 (0.39) HTR2AKDM4EALDH1A1LMNAMAPT
SCHEMBL27777789 0.75 CYP3A4 (0.41) HTR2ANPC1ALDH1A1LMNAMAPT
SCHEMBL28568282 0.73 MEN1 (0.48) NPC1ALDH1A1LMNAMAPTRAB9A
SCHEMBL29065719 0.72 MGLL (0.44) HTR2AKDM4EALDH1A1LMNAHPGD
SCHEMBL19566504 0.70 HSD17B10 (0.50) HTR2AKDM4ENPC1ALDH1A1LMNA
Benzidine SCHEMBL28084252 0.69 ALDH1A1 (0.67) KDM4ENPC1ALDH1A1LMNAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020132133-A1 ELECTROLUMINESCENT DEVICE HAVING AN ORGANIC LAYER INCLUDING POLYIMIDE DONGJIN SEMICHEM CO., LTD. (KR) 2002-09-19 US claimed
US-20020098378-A1 Electroluminescent device having an organic layer including polyimide NESS CO., LTD. 2002-07-25 US claimed
US-6497969-B2 LUMINOUS EFFICIENCY, STABILITY AND DURABILITY NESSDISPLAY CO., LTD. (KR) 2002-12-24 US disclosed
US-20020132133-A1 ELECTROLUMINESCENT DEVICE HAVING AN ORGANIC LAYER INCLUDING POLYIMIDE DONGJIN SEMICHEM CO., LTD. (KR) 2002-09-19 US disclosed
US-20020098378-A1 Electroluminescent device having an organic layer including polyimide NESS CO., LTD. 2002-07-25 US disclosed