Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NT5E | P21589 | 1/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.38 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.38 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | DRD3 | P35462 | 1/20 | 0.34 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7523468 | 0.89 | NT5E (0.37) | NT5EDRD2DRD3SGMS2MEN1 | |
| SCHEMBL7521561 | 0.89 | NT5E (0.43) | NT5EPTPN1CXCR2TP53TDP1 | |
| SCHEMBL7520923 | 0.82 | THRB (0.40) | NT5EPTPN1CXCR2TP53MEN1 | |
| SCHEMBL5838298 | 0.77 | KDM4E (0.40) | NT5EPTPN1PTPN2CXCR2TP53 | |
| SCHEMBL5838160 | 0.77 | ALDH1A1 (0.43) | NT5ETP53MEN1KMT2A | |
| SCHEMBL7521067 | 0.77 | PTPN1 (0.47) | PTPN1PTPN2 | |
| SCHEMBL7524872 | 0.77 | MAPT (0.42) | NT5EMEN1KMT2A | |
| SCHEMBL5837805 | 0.76 | NT5E (0.41) | NT5EPTPN1CXCR2TP53 | |
| SCHEMBL5837927 | 0.76 | NT5E (0.40) | NT5EPTPN1PTPN2CXCR2TP53 | |
| SCHEMBL5837754 | 0.76 | AKR1C2 (0.36) | NT5EPTPN1TDP1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020099073-A1 | Modulators of protein tyrosine phosphatases (PTPases) | NOVO NORDISK A/S (DK) | 2002-07-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020099073-A1 | Modulators of protein tyrosine phosphatases (PTPases) | PTPN1, PTPRO, PTPRS | NT5E 825/4885PTPN1 1/4885PTPN2 14/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.