SCHEMBL7520005

SCHEMBL7520005

CCCCCCCC(S)C(C)CO

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 0.52
CYP2D6 P10635 2/20 0.44
SPHK1 Q9NYA1 2/20 0.44
GMNN O75496 1/20 0.44
POLB P06746 1/20 0.44
THPO P40225 1/20 0.44
MTOR P42345 1/20 0.44
BLM P54132 1/20 0.44
KDM4E B2RXH2 1/20 0.44
TP53 P04637 1/20 0.44
CYP1A2 P05177 1/20 0.44
CYP3A4 P08684 1/20 0.44
MAPT P10636 1/20 0.44
CETP P11597 1/20 0.44
HTT P42858 1/20 0.44
UBE2N P61088 1/20 0.44
OPRM1 P35372 1/20 0.39
ALDH1A1 P00352 1/20 0.39
HSD17B10 Q99714 1/20 0.39
MEN1 O00255 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7922133 0.91 ALDH1A1 (0.44) LMNACYP2D6SPHK1GMNNPOLB
SCHEMBL10643418 0.84 OPRM1 (0.44) LMNASPHK1OPRM1TSHRSMPD1
SCHEMBL9562613 0.82 OPRM1 (0.42) LMNASPHK1OPRM1TSHRSMPD1
SCHEMBL11284058 0.80 LMNA (0.55) LMNACYP2D6SPHK1GMNNPOLB
SCHEMBL3370075 0.79 LMNA (0.58) LMNACYP2D6SPHK1GMNNPOLB
SCHEMBL3364419 0.79 LMNA (0.58) LMNACYP2D6SPHK1GMNNPOLB
SCHEMBL1660059 0.79 LMNA (0.58) LMNACYP2D6SPHK1GMNNPOLB
SCHEMBL6159762 0.79 LMNA (0.58) LMNACYP2D6SPHK1GMNNPOLB
SCHEMBL1019405 0.79 LMNA (0.58) LMNACYP2D6SPHK1GMNNPOLB
SCHEMBL6157389 0.79 LMNA (0.58) LMNACYP2D6SPHK1GMNNPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6028210-A REACTING BORIC ACID WITH AN ALKOXYALKYL SULFIDE TO FORM AN ALICYCLIC THIOALKYL BORATE ESTERS OR A THIOALKYL-SUBSTITUTED CYCLIC META BORATE ESTERS; OIL ADDITIVES FOR LUBRICATING AND POWER TRANSMISSION EXXON CHEMICAL PATENTS, INC. (US) 2000-02-22 US claimed
EP-0979265-B1 LUBRICATING OIL COMPOSITIONS INFINEUM USA LP (US) 2002-02-06 EP disclosed
US-6277794-B1 MIXTURE OF A BORATE ESTER AND DETERGENT INFINEUM USA L.P. 2001-08-21 US disclosed
US-20010003734-A1 Lubricant compositions INFINEUM USA L.P. 2001-06-14 US disclosed
EP-1049758-A1 Lubricant compositions Infineum USA L.P. (US) 2000-11-08 EP disclosed
US-6103672-A Lubricating oil compositions EXXON CHEMICAL PATENTS, INC. (US) 2000-08-15 US disclosed
US-6028210-A REACTING BORIC ACID WITH AN ALKOXYALKYL SULFIDE TO FORM AN ALICYCLIC THIOALKYL BORATE ESTERS OR A THIOALKYL-SUBSTITUTED CYCLIC META BORATE ESTERS; OIL ADDITIVES FOR LUBRICATING AND POWER TRANSMISSION EXXON CHEMICAL PATENTS, INC. (US) 2000-02-22 US disclosed
EP-0979265-A1 LUBRICATING OIL COMPOSITIONS Infineum USA L.P. (US) 2000-02-16 EP disclosed
WO-1999035218-A1 LUBRICANT COMPOSITIONS INFINEUM USA L.P. (US) 1999-07-15 WO disclosed
US-5885943-A ACYCLIC BORATE ESTER OR TRIOXYBOROXIN DERIVATIVE REACTION PRODUCT OF BORIC ACID AND AN ALKYL HYDROXYALKYL SULFIDE COMPOUND; WEAR AND OXIDATION RESISTANCE EXXON CHEMICAL PATENTS INC. (US) 1999-03-23 US disclosed
WO-1998050501-A1 LUBRICATING OIL COMPOSITIONS INFINEUM USA L.P. (GB) 1998-11-12 WO disclosed