Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.40 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.36 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.36 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.33 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.32 |
| ▸ | NOS2 | P35228 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
| ▸ | ZDHHC7 | Q9NXF8 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | PAOX | Q6QHF9 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3157490 | 0.92 | TRPV1 (0.34) | TRPV1SIRT6SIRT1ASAH1CHRM2 | |
| SCHEMBL7801151 | 0.82 | SIRT6 (0.50) | TRPV1SIRT6SIRT1PAOX | |
| SCHEMBL17213387 | 0.80 | SIRT6 (0.47) | SIRT6SIRT1PLA2G2CPLA2G2ATP53 | |
| SCHEMBL12478006 | 0.78 | PLA2G2C (0.46) | SIRT6SIRT1PLA2G2C | |
| SCHEMBL29194376 | 0.77 | FFAR1 (0.51) | SIRT6SIRT1PLA2G2CNFKB1 | |
| SCHEMBL12594196 | 0.76 | SMN1; SMN2 (0.50) | TRPV1SIRT6SIRT1CHRM2CHRM4 | |
| Benzene SCHEMBL9177693 | 0.74 | SIRT6 (0.43) | SIRT6SIRT1PLA2G2CPLA2G2AALDH1A1 | |
| SCHEMBL7085362 | 0.73 | — | — | |
| SCHEMBL12594194 | 0.70 | KMT2A (0.48) | TRPV1SIRT6SIRT1CHRM2CHRM4 | |
| SCHEMBL28663197 | 0.69 | MTNR1A (0.41) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0786087-B1 | POLYPEPTIDE-DENDRIMER COMPLEXES | DADE BEHRING INC (US) | 2002-02-27 | — | — | EP | disclosed |
| US-6083708-A | BRANCHING COMPOUND WITH AT LEAST TWO TERMINI, EACH OF WHICH HAS PREFERENTIAL ENZYME ACTIVITY | DADE BEHRING INC. (US) | 2000-07-04 | — | — | US | disclosed |
| EP-0786087-A1 | POLYPEPTIDE-DENDRIMER COMPLEXES | DADE INTERNATIONAL INC. (US) | 1997-07-30 | — | — | EP | disclosed |
| WO-1997007398-A1 | POLYPEPTIDE-DENDRIMER COMPLEXES | DADE INTERNATIONAL INC. (US) | 1997-02-27 | — | — | WO | disclosed |