Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | SHBG | P04278 | 1/20 | 0.32 |
| ▸ | POLQ | O75417 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | IDH1 | O75874 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL225355 | 0.92 | NPC1 (0.33) | NPC1RAB9ASHBGPOLQCYP3A4 | |
| SCHEMBL29357978 | 0.92 | NPC1 (0.33) | NPC1RAB9ASHBGPOLQCYP3A4 | |
| SCHEMBL769323 | 0.90 | SHBG (0.35) | NPC1RAB9ASHBGCYP3A4CYP2D6 | |
| SCHEMBL7520348 | 0.87 | CNR2 (0.35) | NPC1RAB9A | |
| SCHEMBL28526450 | 0.85 | LMNA (0.35) | NPC1RAB9ASHBGCYP3A4CYP2D6 | |
| SCHEMBL5646334 | 0.85 | GLO1 (0.31) | NPC1RAB9A | |
| SCHEMBL6856174 | 0.84 | POLQ (0.33) | NPC1RAB9ASHBGPOLQKDM4E | |
| SCHEMBL5646861 | 0.84 | S1PR5 (0.35) | CYP3A4CYP2D6KDM4EALDH1A1CYP2C9 | |
| SCHEMBL12337787 | 0.83 | ESR1 (0.36) | POLQ | |
| Benzotriazole SCHEMBL3915546 | 0.83 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020169239-A1 | 2H-benzotriazole UV absorbers substituted with 1,1-diphenylakyl groups and compositions stabilized therewith | WOOD MERVIN G (US) | 2002-11-14 | — | — | US | claimed |
| US-6392056-B1 | FOR THERMOPLASTIC RESINS | CIBA SPECIALTY CHEMICAL CORPORATION | 2002-05-21 | — | — | US | claimed |
| US-6489383-B1 | SUCH AS 2-(2-HYDROXY-3-(1,1-DI(4-2-(BROMOETHOXY)PHENYL) ETHYL)-5-TERT-BUTYLPHENYL)-2H-BENZOTRIAZOLE FOR USE AS STOVING LACQUER, FINISHING ENAMEL FOR AUTOMOBILES | CIBA SPECIALTY CHEMICALS CORPORATION | 2002-12-03 | — | — | US | disclosed |
| US-20020169239-A1 | 2H-benzotriazole UV absorbers substituted with 1,1-diphenylakyl groups and compositions stabilized therewith | WOOD MERVIN G (US) | 2002-11-14 | — | — | US | disclosed |
| US-6392056-B1 | FOR THERMOPLASTIC RESINS | CIBA SPECIALTY CHEMICAL CORPORATION | 2002-05-21 | — | — | US | disclosed |
| WO-2002012204-A1 | 2H-BENZOTRIAZOLE UV ABSORBERS SUBSTITUTED WITH 1,1-DIPHENYLALKYL GROUPS AND COMPOSITIONS STABILIZED THEREWITH | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2002-02-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020169239-A1 | 2H-benzotriazole UV absorbers substituted with 1,1-diphenylakyl groups and compositions stabilized therewith | SUV39H1, SUV39H2, PAH | NPC1 3986/4885RAB9A 4648/4885SHBG 2519/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.